| Gene Symbol |
Cd38
|
| Entrez Gene |
25668
|
| Alt Symbol |
ADPRC 1
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
CD38 molecule
|
| Other Description |
2'-phospho-ADP-ribosyl cyclase|2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase|2'-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase)|CD38H|cADPr hydrolase 1|cyclic ADP-ribose hydrolase 1
|
| Swissprots |
Q64244
|
| Accessions |
EDL99952 Q64244 D29646 BAA06129 D30795 BAA06457 FQ212353 XM_006251072 XP_006251134 NM_013127 NP_037259
|
| Function |
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity.
|
| Subcellular Location |
Membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Spleen, liver, heart, thymus, thyroid gland, ileum, colon, cerebellum, salivary gland, adrenal gland, jejunum, islets of Langerhans and osteoclasts. {ECO:0000269|PubMed:10477767}.
|
| Top Pathways |
Hematopoietic cell lineage, Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Epstein-Barr virus infection
|