| Gene Symbol |
acrB
|
| Entrez Gene |
945108
|
| Alt Symbol |
ECK0456, JW0451, acrE
|
| Species |
Escherichia coli
|
| Gene Type |
protein-coding
|
| Description |
multidrug efflux system protein
|
| Other Description |
-
|
| Swissprots |
P31224 Q2MBW5
|
| Accessions |
AAC73564 NP_414995
|
| Function |
AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates. {ECO:0000269|PubMed:16915237, ECO:0000269|PubMed:16946072, ECO:0000269|PubMed:17194213, ECO:0000269|PubMed:23010927}.
|
| Subcellular Location |
Cell inner membrane {ECO:0000269|PubMed:15228545, ECO:0000269|PubMed:16079137}; Multi- pass membrane protein {ECO:0000269|PubMed:15228545, ECO:0000269|PubMed:16079137}.
|
| Top Pathways |
beta-Lactam resistance, Cationic antimicrobial peptide (CAMP) resistance
|