Ggt1

Gene Symbol Ggt1
Entrez Gene 14598
Alt Symbol CD224, GGT, GGT 1, GGT-1, Ggtp, dwg
Species Mouse
Gene Type protein-coding
Description gamma-glutamyltransferase 1
Other Description gamma-glutamyltranspeptidase 1|glutathione hydrolase 1|leukotriene-C4 hydrolase
Swissprots Q60928
Accessions EDL31902 EDL31903 EDL31904 EDL31905 EDL31906 EDL31907 EDL31908 EDL31909 Q60928 AK079235 BC012969 AAH12969 BU756502 CT010196 CAJ18404 L17331 L17332 L17333 L17334 L17335 L17336 S78533 U30509 AAA97395 XM_006513230 XP_006513293 XM_006513231 XP_006513294 XM_006513232 XP_006513295 XM_011243371 XP_011241673 NM_001305992 NP_001292921 NM_008116 NP_032142
Function Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Indirectly regulates multiple aspects of skeletal biology. {ECO:0000269|PubMed:12810527}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Top Pathways Taurine and hypotaurine metabolism, Glutathione metabolism, Arachidonic acid metabolism, Cyanoamino acid metabolism

Recombinant Gamma-Glutamyltransferase 1 (gGT1) - RPB375Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Gamma-Glutamyltransferase 1 (gGT1) - RPB375Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Gamma-glutamyltranspeptidase 1(Ggt1) - CSB-YP733723MO CSB-EP733723MO CSB-BP733723MO CSB-MP733723MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Gamma-Glutamyltransferase 1 Protein (Recombinant) - abx167263 from Abbexa

Category Protein
Source Mouse
Species Mouse

Gamma-glutamyltranspeptidase 1 (Ggt1), Recombinant Protein - MBS1439391 from MyBioSource

Category Protein
Prices $1,145.00, $1,145.00, $1,380.00, $1,380.00, $1,830.00, $1,830.00, $2,295.00, $2,295.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Recombinant Gamma-Glutamyltransferase 1 (gGT1) - RPU52570 from Biomatik

Category Protein
Prices $189.00, $387.00, $592.00, $705.20
Sizes 10 µg, 50 µg, 100 µg, 200 µg
Source E.coli
Species Mouse

GGT1 Recombinant Protein (OPCD03533) - OPCD03533 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse
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