BMI1

Gene Symbol BMI1
Entrez Gene 648
Alt Symbol FLVI2/BMI1, PCGF4, RNF51
Species Human
Gene Type protein-coding
Description BMI1 proto-oncogene, polycomb ring finger
Other Description B lymphoma Mo-MLV insertion region 1 homolog|BMI1 polycomb ring finger oncogene|BMI1 polycomb ring finger proto-oncogene|flvi-2/bmi-1|murine leukemia viral (bmi-1) oncogene homolog|polycomb complex protein BMI-1|polycomb group RING finger protein 4|polycomb group protein Bmi1|ring finger protein 51
Swissprots Q96F37 P35226 Q5T8Z3 Q16030
Accessions EAW86148 EAW86150 EAW86151 EAW86154 P35226 AI274830 BC011652 AAH11652 BE008203 BT019450 AAV38257 CR456911 CAG33192 DB161566 DB225488 L13689 AAA19873 NM_005180 NP_005171
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. {ECO:0000269|PubMed:16359901, ECO:0000269|PubMed:16714294, ECO:0000269|PubMed:16882984}.
Subcellular Location Nucleus. Cytoplasm.
Top Pathways MicroRNAs in cancer, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

Bmi1 (D20B7) XP ® Rabbit mAb - 6964 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D20B7
Western blot analysis of extracts from various cell lines using Bmi1 (D20B7) XP ® Rabbit mAb.

Bmi1 (D42B3) Rabbit mAb - 5856 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D42B3
Western blot analysis of extracts from various cell lines using Bmi1 (D42B3) Rabbit mAb.

Bmi1 Antibody - 2830 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Bmi1 Antibody.

Bmi1 (DC9) Mouse mAb - 5855 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone DC9
Western blot analysis of extracts from various cell lines using Bmi1 (DC9) Mouse mAb.

Bmi-1 (F-9) - sc-390443 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Bmi-1 (F-9): sc-390443. Western blot analysis of Bmi-1 expression in HeLa whole cell lysate.

Bmi-1 (K-18) - sc-30944 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Bmi-1 (C-20) - sc-8906 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Bmi-1 (C-20): sc-8906. Western blot analysis of human recombinant Bmi-1 (A) and expression in K-562 nuclear extract (B).

Bmi-1 (H-99) - sc-10745 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Bmi-1 (H-99): sc-10745. Western blot analysis of Bmi-1 expression in K-562 nuclear extract.

Bmi-1 (S-15) - sc-30943 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BMI1 / PCGF4 Antibody (Internal, Biotin) - LS-C141367 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BMI1 / PCGF4 Antibody (aa1-100) - LS-C49129 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Bmi1 protein in skeletal muscle.

Anti-BMI1 / PCGF4 Antibody (aa142-159) - LS-C148975 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-BMI1 / PCGF4 Antibody (clone 229F6) - LS-C150548 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 229F6

Anti-BMI1 / PCGF4 Antibody (aa181-230) - LS-C146455 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BMI1 antibody LS-C146455 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.

Anti-BMI1 / PCGF4 Antibody (aa270-320) - LS-C148527 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of BMI1 in skeletal muscle lysate. Lane 1 shows pre-immune sera. Lanes 2, 3 and 4 show LS-C148527 tested on human, mouse and rat muscle lysate at 2 ug/ml, respectively. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

Anti-BMI1 / PCGF4 Antibody (clone LLBmi1-1, DY650) - LS-C181006 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LLBmi1-1

Anti-BMI1 / PCGF4 Antibody (clone LLBmi1-1, Biotin) - LS-C181005 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LLBmi1-1

Anti-BMI1 / PCGF4 Antibody (clone LLBmi1-1, DY488) - LS-C181007 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LLBmi1-1

Anti-BMI1 / PCGF4 Antibody (clone LLBmi1-1, HRP) - LS-C181008 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LLBmi1-1

Anti-BMI1 / PCGF4 Antibody (clone LLBmi1-1, DY550) - LS-C181009 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LLBmi1-1

Anti-BMI1 / PCGF4 Antibody (clone 2704C2a) - LS-C184479 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2704C2a

Anti-BMI1 / PCGF4 Antibody (aa96-326) - LS-C149862 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
BMI-1 in K562 Human Cell Line. BM I-1 was detected in immersion fixed K562 human chronic myelogenous leukemia cell line using 10 ug/ml Goat Anti-Human BMI-1 Antigen Affinity-purified Polyclonal Antibody for 3 hours at room temperature. Cells were stained with the NorthernLights 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue).

Anti-BMI1 / PCGF4 Antibody (Internal) - LS-C19577 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of BMI-1 in K562 cells with LS-C19577 at 10 µg/ml.

Anti-BMI1 / PCGF4 Antibody - LS-C156832 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
BMI1 western blot of K562 cell line lysates (35 ug/lane). The BMI1 antibody detected the BMI1 protein (arrow).

Anti-BMI1 / PCGF4 Antibody (aa136-163) - LS-C164303 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Mouse Bmi1 antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The Mouse Bmi1 antibody detected the Mouse Bmi1 protein (arrow).
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