| Gene Symbol |
Milr1
|
| Entrez Gene |
59105
|
| Alt Symbol |
Mca32
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
mast cell immunoglobulin-like receptor 1
|
| Other Description |
MCA-32|allergin-1|allergy inhibitory receptor 1|mast cell Ag-32|mast cell antigen 32|surface protein MCA-32
|
| Swissprots |
Q62875
|
| Accessions |
EDM06409 EDM06410 Q62875 U39546 AAC52339 XM_008768388 XP_008766610 XM_008768389 XP_008766611 NM_021585 NP_067596
|
| Function |
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE- mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:7499870}; Single-pass type I membrane protein {ECO:0000269|PubMed:7499870}.
|
| Tissue Specificity |
Mast cell-specific. Expressed in primary and transformed mast cells. {ECO:0000269|PubMed:7499870}.
|