SOD1

Gene Symbol SOD1
Entrez Gene 6647
Alt Symbol ALS, ALS1, HEL-S-44, IPOA, SOD, hSod1, homodimer
Species Human
Gene Type protein-coding
Description superoxide dismutase 1, soluble
Other Description Cu/Zn superoxide dismutase|SOD, soluble|epididymis secretory protein Li 44|indophenoloxidase A|superoxide dismutase [Cu-Zn]|superoxide dismutase, cystolic
Swissprots Q16711 P00441 Q6NR85 Q16840 Q16669 A6NHJ0 Q16839 Q16838 D3DSE4
Accessions AAB05661 AAB05662 AAB59626 AAB59627 AAC41773 AAV80422 AHL39099 AHW49383 AHW49384 AHW49385 AHW49386 AHW49387 AHW49388 CAA25915 CAA25916 CAA25917 CAA25918 CAA25919 CAA64520 CBX86766 CCQ42983 EAX09889 EAX09890 P00441 AK312116 BAG35052 AV756797 AY049787 AAL15444 AY450286 AAR21563 BC001034 AAH01034 BT006676 AAP35322 CA448539 CR450355 CAG29351 CR541742 CAG46542 EF143990 ABL96474 EF151142 ABL96616 EU794661 ACJ13715 W17182 X02317 CAA26182 NM_000454 NP_000445
Function Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Subcellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria.
Top Pathways Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases, Peroxisome

SOD1 Antibody - 2770 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa, MCF7 and T47D cell lines, using SOD1 Antibody.

SOD1 (71G8) Mouse mAb - 4266 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 71G8
Western blot analysis of extracts from various cell lines using SOD1 (71G8) Mouse mAb.

SOD-1 (24) - sc-101523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SOD-1 (24): sc-101523. Western blot analysis of SOD-1 expression in HeLa whole cell lysate.

SOD-1 (B-1) - sc-271014 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SOD-1 (B-1): sc-271014. Western blot analysis of SOD-1 expression in non-transfected: sc-117752 (A) and mouse SOD-1 transfected: sc-123711 (B) 293T whole cell lysates.

SOD-1 (C-17) - sc-8637 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SOD-1 (C-17): sc-8637. Western blot analysis of SOD-1 expression in HeLa (A), Jurkat (B), Hep G2 (C), DU 145 (D), Hs68 (E) and CCD-1064Sk (F) whole cell lysates.

SOD-1 (FL-154) - sc-11407 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SOD-1 (FL-154): sc-11407. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

SOD-1 (G-11) - sc-17767 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SOD-1 (G-11): sc-17767. Western blot analysis of SOD-1 expression in CCD-1064Sk (A) and Hs68 (B) whole cell lysates.

SOD-1 (N-19) - sc-8636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SOD-1 (N-19): sc-8636. Western blot analysis of SOD-1 expression in HeLa (A), Jurkat (B), Hep G2 (C), DU 145 (D), Hs68 (E) and CCD-1064Sk (F) whole cell lysates.

SOD-1 (V-17) - sc-34015 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SOD-1 (V-17): sc-34015. Western blot analysis of SOD-1 expression in Hep G2 (A), DU 145 (B) and CCD-1064Sk (C) whole cell lysates.

SOD-1 (72B1) - sc-58421 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
SOD-1 (72B1): sc-58421. Western blot analysis of SOD-1 expression in HeLa (A), Jurkat (B), Hep G2 (C), DU 145 (D), Hs68 (E) and CCD-1064Sk (F) whole cell lysates.

Anti-Cu/Zn SOD1 antibody (Biotin) - ab195505 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cu/Zn SOD1 antibody (Biotin) (ab195505) at 1/1000 dilutionLane 1 : Rat liver tissue lysateLane 2 : Mouse liver tissue lysateLane 3 : HeLa cell lysateLane 4 : Rat brain tissue extractLane 5 : Mouse brain tissue extract

Anti-Superoxide Dismutase 1 antibody - ab16831 from Abcam

Prices $401.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Superoxide Dismutase 1 antibody - ab52950 from Abcam

Prices $391.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Superoxide Dismutase 1 antibody (ab52950) at 1/5000 dilution + Jurkat cell lysate at 10 µgSecondarygoat anti-rabbit HRP at 1/2000 dilution

Anti-Superoxide Dismutase 1 antibody - ab21968 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab21968, staining cortical neurons and glial cells in Dementia with Lewy bodies.

Anti-Superoxide Dismutase 1 antibody - ab88404 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Superoxide Dismutase 1 antibody (ab88404) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lane 5 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 6 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 7 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Superoxide Dismutase 1 antibody - ab45777 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Superoxide Dismutase 1 antibody (ab45777) at 0.5 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate (ab7899)Lane 3 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate (ab7909)Lane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate (ab7902)Lane 5 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate (ab7900)Lane 6 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 7 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell LysateLane 8 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate with Human Superoxide Dismutase 1 peptide (ab46993) at 1 µgLane 9 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate (ab7899) with Human Superoxide Dismutase 1 peptide (ab46993) at 1 µg/mlLane 10 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate (ab7909) with Human Superoxide Dismutase 1

Anti-Superoxide Dismutase 1 antibody - ab8866 from Abcam

Prices $378.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal
Immunofluorescence analysis of retinal tissue taken from XBP1+/+ or XBP-/- mice. Superoxide Dismutase 1 was stained using ab8866 at 1/200 dilution..

Anti-Superoxide Dismutase 1 antibody - ab89786 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Superoxide Dismutase 1 antibody (ab89786) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-Superoxide Dismutase 1 antibody - ab93329 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Superoxide Dismutase 1 antibody (ab93329) at 1/100 dilution + Jurkat cell line lysate at 35 µg

Anti-Superoxide Dismutase 1 antibody - ab21199 from Abcam

Prices $370.00
Sizes 500 µl
Host Sheep
Clonality Polyclonal

Anti-Superoxide Dismutase 1 antibody [6F5] - ab86454 from Abcam

Host Mouse
Clonality Monoclonal
Clone 6F5
All lanes : Anti-Superoxide Dismutase 1 antibody [6F5] (ab86454) at 1/500 dilutionLane 1 : A431 cell lysateLane 2 : HeLa cell lysate

Anti-Superoxide Dismutase 1 antibody [72B1] - ab16948 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 72B1
IP with ab16958 of SOD1 from HeLa cell lysate.Lane 1 - inputLane 2 - IP with ab16958Immunoblotting with polyclonal to SOD16831.

Anti-Superoxide Dismutase 1 antibody [8A1] - ab16950 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8A1
IP of SOD1 from HeLa cell lysateLane 1 - inputLane 2 - IP with ab16950Immunoblot with polyclonal to SOD1 (ab16831)

Anti-Superoxide Dismutase 1 antibody [EP1727Y] - ab51254 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1727Y
Anti-Superoxide Dismutase 1 antibody [EP1727Y] (ab51254) at 1/50000 dilution + Jurkat cell lysate at 10 µgSecondaryGoat anti-rabbit HRP labeled at 1/2000 dilution

Anti-Superoxide Dismutase 1 antibody [EP1727Y] (Alexa Fluor® 488) - ab199733 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1727Y
ab199733 staining Superoxide Dismutase 1 in HeLa cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab at a 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at a 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HeLa cells fixed with 4% formaldehyde (10 min).
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