CYP4A11

Gene Symbol CYP4A11
Entrez Gene 1579
Alt Symbol CP4Y, CYP4A2, CYP4AII
Species Human
Gene Type protein-coding
Description cytochrome P450, family 4, subfamily A, polypeptide 11
Other Description 20-HETE synthase|20-hydroxyeicosatetraenoic acid synthase|CYPIVA11|P450HL-omega|alkane-1 monooxygenase|cytochrome P-450HK-omega|cytochrome P450 4A11|cytochrome P450, subfamily IVA, polypeptide 11|cytochrome P450HL-omega|fatty acid omega-hydroxylase|lauric acid omega-hydroxylase
Swissprots Q06766 Q8IWY5 Q16865 Q5VSP8 Q02928 Q86SU6 Q16866
Accessions AAO16078 AAQ56847 Q02928 AK298267 BAG60530 AK298413 BAG60640 BC022851 BC041158 AAH41158 CD014132 D13705 BAA02864 D26481 BAA05491 L04751 AAA58436 S67580 AAB29502 S67581 AAB29503 X71480 CAA50586 XM_005270539 XP_005270596 XM_011540826 XP_011539128 XM_011540827 XP_011539129 XM_011540828 XP_011539130 XM_011540829 XP_011539131 XM_011540830 XP_011539132 XR_246241 XR_246242 NM_000778 NP_000769
Function Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE). {ECO:0000269|PubMed:15611369, ECO:0000269|PubMed:1739747, ECO:0000269|PubMed:7679927}.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Kidney and liver. {ECO:0000269|PubMed:7679927}.
Top Pathways Vascular smooth muscle contraction, Arachidonic acid metabolism, Fatty acid degradation, Retinol metabolism

CYP4A11 (M25-P2A10) - sc-101385 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP4A11 (M25-P2A10): sc-101385. Western blot analysis of CYP4A11 expression in human liver microsomes.

CYP4A11 (N-14) - sc-323772 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Cytochrome P450 4A antibody - ab3573 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab3573 labelling Cytochrome P450 4A (green) in the cytoplasm and membrane of H-4-II-E cells (right), compared to control (left), by Immunocytochemistry/Immunofluorescence. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were incubated with the primary antibody (1:100 in 3% BSA-PBS) overnight at 4 ºC. A DyLight-conjugated anti-rabbit was used as the secondary antibody. Red (phalloidin) - F-actin, Blue - nuclei. Images were taken at a magnification of 60x.

Anti-Cytochrome P450 4A antibody - ab96853 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome P450 4A antibody (ab96853) at 1/100 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Cytochrome P450 4A antibody [EPR8276] - ab140635 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8276
All lanes : Anti-Cytochrome P450 4A antibody [EPR8276] (ab140635) at 1/1000 dilutionLane 1 : Mouse liver lysateLane 2 : Rat liver lysateLane 3 : Human fetal kidney lysateLane 4 : Human fetal liver lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Cytochrome P450 4A antibody - C-terminal - ab82857 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 4A antibody - C-terminal (ab82857) at 1/50 dilution + NCI-H460 cell line lysates

Anti-Cytochrome P450 4A11/22 antibody - ab152000 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 4A11/22 antibody (ab152000) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-Cytochrome P450 4A11/22 antibody - ab110746 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome P450 4A11/22 antibody (ab110746) at 1/500 dilutionLane 1 : COLO205 cell lysateLane 2 : COLO205 cell lysate with blocking peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-CYP4A11 Antibody (aa431-445) - LS-C64211 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP4A11 Antibody - LS-C341798 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP4A11 Antibody (C-Terminus) - LS-C97499 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Confocal immunofluorescent of CYP4A11 (4A22) Antibody with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Anti-CYP4A11 Antibody (aa48-316) - LS-C185545 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded mixed OVCA using CYP4A11 antibody at 1:100 dilution.

Cytochrome P450 4A Antibody - NBP1-31427 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cytochrome P450 4A Antibody - NBP2-16081 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Cytochrome P450 4A Antibody [NBP2-16081] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE gel, diluted at 1:1000.

Cytochrome P450 4A Antibody - H00001579-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Cytochrome P450 4A Antibody [H00001579-B01P] - Analysis of CYP4A11 expression in transfected 293T cell line by CYP4A11 polyclonal antibody.  Lane 1: CYP4A11 transfected lysate(23.76 KDa). Lane 2: Non-transfected lysate.

Cytochrome P450 4A Polyclonal Antibody - bs-5054R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded mouse kidney labeled with Anti-CYP4A1 Polyclonal Antibody, Unconjugated (bs-5054R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-CYP4A11 antibody produced in rabbit - SAB2702082 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CYP4A11: <B>Cat. No. SAB2702082</B>: Immunohistochemical analysis of paraffin-embedded hepatoma, using CYP4A11 antibody at 1:500 dilution.

Anti-CYP4A11 (4A22) (C-term) antibody produced in rabbit - SAB1300945 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP4A11 (4A22) (C-term) Antibody: <B>Cat. No. SAB1300945</B>: CYP4A11 in NCI-H460 cell line lysates with Anti-CYP4A11 (4A22) (C-term) Antibody at 4.0 μg/mL.

Anti-CYP4A11 antibody produced in mouse - SAB1405690 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP4A11: <B>Cat. No. SAB1405690</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~23.8 kDa using CYP4A11 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-CYP4A11 (N-term) antibody produced in rabbit - SAB1300944 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP4A11 (N-term) Antibody: <B>Cat. No. SAB1300944</B>: CYP4A11 in Jurkat cell line lysates with Anti-CYP4A11 (N-term) Antibody at 4.0 μg/mL.

CYP4A11-4A22-Antibody-C-term - AP7884b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-CYP4A11 (4A22) Antibody (C-term) (Cat.#AP7884b) in NCI-H460 cell line lysates (35ug/lane).CYP4A11(arrow) was detected using the purified Pab.

CYP4A11 Antibody - C-terminal region (OAAB04961) - OAAB04961 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CYP4A11 antibody [N1C1] - GTX103518 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-CYP4A11 antibody [N1C1] used in ICC/IF. GTX103518

CYP4A11 antibody [N3C3] - GTX114353 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-CYP4A11 antibody [N3C3] used in ICC/IF. GTX114353

Cytochrome P450 4A antibody - GTX79175 from GeneTex

Prices $319.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 4A antibody used in Western blot. GTX79175
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