SOS1

Gene Symbol SOS1
Entrez Gene 6654
Alt Symbol GF1, GGF1, GINGF, HGF, NS4
Species Human
Gene Type protein-coding
Description son of sevenless homolog 1 (Drosophila)
Other Description SOS-1|gingival fibromatosis, hereditary, 1|guanine nucleotide exchange factor|son of sevenless homolog 1
Swissprots Q07889 A8K2G3 B4DXG2
Accessions AAF04460 AAM22406 AAX93186 AAY24202 CBX55730 EAX00350 EAX00351 EAX00352 EAX00353 Q07889 AB209140 BAD92377 AK290228 BAF82917 AK301960 BAG63374 AL833457 AV702692 BC140215 AAI40216 L13857 AAA35913 XM_005264515 XP_005264572 XM_011533060 XP_011531362 XM_011533061 XP_011531363 XM_011533062 XP_011531364 XM_011533063 XP_011531365 XM_011533064 XP_011531366 XM_011533065 XP_011531367 XM_011533066 XP_011531368 NM_005633 NP_005624
Function Promotes the exchange of Ras-bound GDP by GTP. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in gingival tissues. {ECO:0000269|PubMed:11868160}.
Top Pathways Alcoholism, Prolactin signaling pathway, PI3K-Akt signaling pathway, MicroRNAs in cancer, Estrogen signaling pathway

SOS1 Antibody - 5890 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using SOS1 Antibody.

SOS1 (D3T7T) Rabbit mAb - 12409 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3T7T
Western blot analysis of extracts from various cell lines using SOS1 (D3T7T) Rabbit mAb.

Sos 1 (E-6) - sc-376843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sos 1 (E-6): sc-376843. Western blot analysis of Sos 1 expression in K-562 whole cell lysate.

Sos 1 (E-11) - sc-55528 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sos 1 (E-11): sc-55528. Western blot analysis of Sos 1 expression in K-562 whole cell lysate.

Sos 1 (G-12) - sc-376789 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sos 1 (G-12): sc-376789. Western blot analysis of Sos 1 expression in K-562 whole cell lysate.

Sos 1 (H-122) - sc-10803 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Sos 1 (H-122): sc-10803. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tumor showing cytoplasmic staining (A). Immunofluorescence staining of methanol-fixed K-562 cells showing cytoplasmic localization (B).

Sos 1 (25) - sc-136235 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
Sos 1 (25): sc-136235. Western blot analysis of Sos 1 expression in PC-12 whole cell lysate.

Sos 1 (A-9) - sc-17793 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sos 1 (A-9): sc-17793. Western blot analysis of Sos 1 expression in K-562 (A), NIH/3T3 (B) and KNRK (C) whole cell lysates.

Sos 1 (C-23) - sc-256 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Sos 1 (C-23): sc-256. Western blot analysis of Sos 1 p170 expression in NIH/3T3 (A) and KNRK (B) whole cell lysates.

Sos 1/2 (D-21) - sc-259 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Sos 1/2 (D-21): sc-259. Western blot analysis of Sos isoform expression in A-431 (A), K-562 (B) and NIH/3T3 (C) whole cell lysates.

Anti-SOS1 antibody - ab35702 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of SOS1 staining in Human Placenta formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab35702, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-SOS1 antibody - ab111298 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab111298, at 3.75µg/ml, staining SOS1 in formalin-fixed, paraffin-embedded Human Liver tissue by Immunohistochemistry.

Anti-SOS1 antibody [AF3F11] - ab82429 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AF3F11
All lanes : Anti-SOS1 antibody [AF3F11] (ab82429) at 1/1000 dilutionLane 1 : HeLa cell lysatesLane 2 : MOLT4 cell lysatesLane 3 : HepG2 cell lysatesLane 4 : NIH3T3 cell lysatesLane 5 : PC12 cell lysates

Anti-SOS1 antibody [EPR7480] - ab140621 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7480
Immunohistochemical analysis of paraffin-embedded Human ovarian carcinoma tissue labelling SOS1 with ab140621 at 1/100 dilution.

Anti-SOS1 antibody [SOS-1] - ab64595 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone SOS-1
ICC/IF image of ab64595 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab64595, 10µg/ml) overnight at +4°C. The secondary antibody (green) was ab96879, DyLight® 488 goat anti-mouse IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM

Anti-SOS1 antibody - Carboxyterminal end - ab50519 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SOS1 Antibody (aa1243-1258) - LS-C10294 from LifeSpan Bioscience

Prices $475.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-SOS1 Antibody - LS-C132160 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SOS1 Antibody (clone SOS-1) - LS-C188432 from LifeSpan Bioscience

Prices $290.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone SOS-1

Anti-SOS1 Antibody (aa1283-1333) - LS-C286087 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SOS1 Antibody (aa1025-1075) - LS-C288667 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SOS1 Antibody (clone 4C1) - LS-C198243 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C1
Detection limit for recombinant GST tagged SOS1 is 0.1 ng/ml as a capture antibody.

Anti-SOS1 Antibody (aa353-402) - LS-C170398 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SOS1 Antibody - LS-C137293 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SOS1 / HGF Antibody (Internal) IHC-plus™ - LS-B4169 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-SOS1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4169 concentration 3.75 ug/ml.
Search more