icmA-2

Gene Symbol icmA-2
Entrez Gene 8619243
Alt Symbol DDBDRAFT_0217410, DDBDRAFT_0252724, DDB_0217410, DDB_0252724
Species Dictyostelium discoideum
Gene Type protein-coding
Description prenylcysteine methyltransferase
Other Description protein-S-isoprenylcysteine O-methyltransferase
Swissprots Q86AM7 Q558K8 Q8T623
Accessions XM_639264 XP_644356
Function Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development. {ECO:0000269|PubMed:17699599}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Terpenoid backbone biosynthesis

Protein-S-isoprenylcysteine O-methyltransferase (icmt-1), Recombinant Protein - MBS7017401 from MyBioSource

Category Protein
Prices $1,055.00, $2,040.00, $3,245.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Dictyostelium discoideum
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