DAD1

Gene Symbol	DAD1
Entrez Gene	1603
Alt Symbol	OST2
Species	Human
Gene Type	protein-coding
Description	defender against cell death 1
Other Description	DAD-1|dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1|oligosaccharyl transferase subunit DAD1|oligosaccharyltransferase 2 homolog|oligosaccharyltransferase subunit 2 (non-catalytic)
Swissprots	P61803 D3DS25 Q6FGA3
Accessions	AAB58540 AAO74827 EAW66252 EAW66253 P61803 AK223129 BAD96849 BC007403 AAH07403 BC009798 AAH09798 BC038575 BP198316 CR407682 CAG28610 CR542204 CAG47001 D15057 BAA03650 DQ892868 ABM83794 DQ896117 ABM87116 NM_001344 NP_001335
Function	Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways	N-Glycan biosynthesis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DAD1 full length protein - ab114803 from Abcam Category Protein Source Wheat germ Species Human

DAD1 Antibody Blocking Peptide - LS-E5029 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DAD1 Antibody Blocking Peptide - LS-E30067 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human DAD1 Protein - H00001603-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DAD1 Blocking Peptide - NBP1-77197PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

DAD1-Antibody-C-term-Blocking-Peptide - BP17433b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DAD1 Peptide - GTX85083-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Human DAD1 protein - orb245166 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

DAD1 - H00001603-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DAD1 - H00001603-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DAD1 Control Peptide - AP30271CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

DAD1 Peptide - 3313P from ProSci Category Peptide Species Human

DAD1 fusion protein - Ag0814 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human DAD1 - DAD1-27092TH from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human DAD1, GST-tagged - DAD1-11817H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase - CSB-EP031244h CSB-BP031244h CSB-MP031244h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein - CSB-RP031244h from Cusabio Category Protein Species Human

DAD1 Recombinant Protein Antigen - NBP1-82466PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DAD1 Peptide, Human - M34GP04013H from Creative Peptides Category Peptide Source Synthetic. Species Human

Defender against cell death 1 (DAD1), Recombinant Protein - MBS1002078 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell

Defender against cell death 1 (DAD1), Recombinant Protein - MBS1223573 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell

Defender against cell death 1 (DAD1), Recombinant Protein - MBS7013613 from MyBioSource Category Protein Prices $945.00, $1,925.00, $3,135.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression

Defender against cell death 1 (DAD1), Recombinant Protein - MBS7013616 from MyBioSource Category Protein Prices $945.00, $1,925.00, $3,135.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression

Defender against cell death 1 (DAD1), Recombinant Protein - MBS7013617 from MyBioSource Category Protein Prices $945.00, $1,925.00, $3,130.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression

Defender against cell death 1 (DAD1), Recombinant Protein - MBS7013619 from MyBioSource Category Protein Prices $950.00, $1,930.00, $3,135.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression

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