CDC42

Gene Symbol CDC42
Entrez Gene 998
Alt Symbol CDC42Hs, G25K
Species Human
Gene Type protein-coding
Description cell division cycle 42
Other Description G25K GTP-binding protein|GTP binding protein, 25kDa|GTP-binding protein, 25kD|cell division control protein 42 homolog|dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD))|dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD))|growth-regulating protein|small GTP binding protein CDC42
Swissprots Q9UDI2 Q7L8R5 P60953 P21181 P25763
Accessions AAT70721 CAE93985 CAI61729 EAW95002 EAW95003 EAW95004 EAW95005 EAW95006 EAW95007 EAW95008 EAW95009 P60953 AF498962 AAM21109 AF498963 AAM21110 AK297465 BAG59887 AK303994 BAG64911 AK311375 AK316449 BAH14820 AL121734 CAB57325 AL121735 CAB57326 AL121736 CAB57327 AL121737 CAB57328 BC002711 AAH02711 BC003682 AAH03682 BC018266 AAH18266 BC018622 BM684474 BP871988 DQ596760 DQ891195 ABM82121 DQ894377 ABM85303 M35543 AAA52494 M57298 AAA52592 NM_001039802 NP_001034891 NM_001791 NP_001782 NM_044472 NP_426359
Function Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. {ECO:0000269|PubMed:14978216, ECO:0000269|PubMed:15642749, ECO:0000269|PubMed:17038317}.
Subcellular Location Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase. Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells. Its localization is regulated by the activities of guanine nucleotide exchange factor ECT2 and GTPase activating protein RACGAP1. Colocalizes with NEK6 in the centrosome.
Top Pathways Adherens junction, Endocytosis, Rap1 signaling pathway, Chemokine signaling pathway, Non-alcoholic fatty liver disease (NAFLD)

Cdc42 Activation Assay Kit - ab173238 from Abcam

Category Cellular Assay
MEF cells were treated with (lane 2) or without EGF (lane 1).Top Panel: Cell lysates were incubated with an anti-active Cdc42 monoclonal antibody. The precipitated active Cdc42 was immunoblotted with the anti-Cdc42 rabbit polyclonal antibody.Bottom Panel: Western blot of the cell lysates used (5% of that used in the top panel) with the anti-Cdc42 rabbit polyclonal antibody provided in the kit.

Human CDC42 ELISA Kit (Sandwich ELISA) - LS-F9126 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 0.064 ng/ml
Range 0.156-10 ng/ml

Human CDC42 ELISA Kit - abx151009 from Abbexa

Category ELISA Kit
Sensitivity 0.053 ng/ml
Range 0.156 ng/ml - 10 ng/ml

Cell division control protein 42 homolog (CDC42), Human, ELISA Kit - E01C1514 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Cell division control protein 42 homolog, CDC42, Human, ELISA Kit - E0321h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 15.6-1000 pg/mL

Ubiquitin Conjugating Enzyme E2L3 (UBE2L3), Human, ELISA Kit - SEE602Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 0.072ng/mL
Range 0.156-10ng/mL

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7229467 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7246889 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7235643 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7205498 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7214724 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7224720 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7211423 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7202990 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7219424 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7238627 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7238886 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell division control protein 42 homolog (CDC42), ELISA Kit - MBS7246826 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell Division Cycle Protein 25, ELISA Kit - MBS080390 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell Division Cycle Protein 25, ELISA Kit - MBS069642 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell Division Cycle Protein 25, ELISA Kit - MBS074001 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell Division Cycle Protein 25, ELISA Kit - MBS091154 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell Division Cycle Protein 25, ELISA Kit - MBS102436 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell Division Cycle Protein 25, ELISA Kit - MBS093736 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell Division Cycle Protein 25, ELISA Kit - MBS081196 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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