C8G
| Gene Symbol | C8G |
|---|---|
| Entrez Gene | 733 |
| Alt Symbol | C8C |
| Species | Human |
| Gene Type | protein-coding |
| Description | complement component 8, gamma polypeptide |
| Other Description | complement component C8 gamma chain |
| Swissprots | Q5SQ07 Q14CU0 P07360 Q14CT8 |
| Accessions | AAA18482 EAW88316 P07360 AW663384 BC113624 AAI13625 BC113626 AAI13627 BM852158 BX282392 HQ258743 ADR83494 M17263 AAA51888 M17999 AAA51863 X06465 CAA29773 XR_245338 NM_000606 NP_000597 |
| Function | C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. |
| Subcellular Location | Secreted. |
| Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis |
C8γ (V-14) - sc-107178 from Santa Cruz Biotechnology
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C8γ (C-14) - sc-107174 from Santa Cruz Biotechnology
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C8γ (S-13) - sc-107176 from Santa Cruz Biotechnology
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Anti-C8G antibody [EPR11274] - C-terminal - ab181182 from Abcam
![All lanes : Anti-C8G antibody [EPR11274] - C-terminal (ab181182) at 1/1000 dilutionLane 1 : Human colon cancer lysateLane 2 : Human plasmaLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_1/18580_ab181182-214706-ab181182WB.jpg)
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Anti-Complement C8G Antibody (aa56-105) - LS-C201401 from LifeSpan Bioscience
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Complement C8A/B/G Antibody (056B-373) - NB100-64340 from Novus Biologicals
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C8G Antibody - NBP2-14422 from Novus Biologicals
![Western Blot: C8G Antibody [NBP2-14422] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted)](http://www.bioprodhub.com/system/product_images/ab_products/5/sub_9/5929_C8G%2520Antibody-Western%2520Blot-NBP2-14422-img0003.jpg)
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Complement C8A/B/G Antibody (056B-373) [PerCP] - NB100-64340PCP from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [Allophycocyanin] - NB100-64340APC from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [DyLight 488] - NB100-64340G from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [DyLight 755] - NB100-64340IR from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [DyLight 350] - NB100-64340UV from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [PE] - NB100-64340PE from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [DyLight 405] - NB100-64340V from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [7C] - NB100-64340V2 from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [Alexa Fluor (R) 700] - NB100-64340AF700 from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [Alexa Fluor (R) 647] - NB100-64340AF647 from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [Alexa Fluor (R) 488] - NB100-64340AF488 from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [Alexa Fluor (R) 405] - NB100-64340AF405 from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [DyLight 405LS] - NB100-64340V3 from Novus Biologicals
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Complement C8A/B/G Antibody (056B-373) [DyLight 680] - NB100-64340FR from Novus Biologicals
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Anti-C8G antibody produced in rabbit - HPA046269 from Sigma-Aldrich
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C8G Antibody (OASA01020) - OASA01020 from Aviva Systems Biology
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C8G Antibody - N-terminal region (ARP41773_P050) - ARP41773_P050 from Aviva Systems Biology
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C8G antibody [N1C3] - GTX120741 from GeneTex
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