EFNB2

Gene Symbol EFNB2
Entrez Gene 1948
Alt Symbol EPLG5, HTKL, Htk-L, LERK5
Species Human
Gene Type protein-coding
Description ephrin-B2
Other Description HTK ligand|LERK-5|eph-related receptor tyrosine kinase ligand 5|ligand of eph-related kinase 5
Swissprots P52799 Q5JV56
Accessions CAD91556 EAX09085 P52799 BC069342 AAH69342 BC074856 AAH74856 BC074857 AAH74857 BC105955 AAI05956 BC105956 AAI05957 BC105957 AAI05958 BG741114 BQ029549 BQ433342 BQ708550 BU622947 CB998384 DR004737 HQ448461 ADQ32941 L38734 AAC41752 U16797 AAA99707 U81262 AAD03786 NM_004093 NP_004084
Function Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons. {ECO:0000269|PubMed:12734395}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Lung and kidney.
Top Pathways Axon guidance

ephrin-B2 (F-2) - sc-398735 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ephrin-B2 (F-2): sc-398735. Western blot analysis of ephrin-B2 expression in HT-29 (A), HUV-EC-C (B) and RT-4 (C) whole cell lysates.

ephrin-B2 (C-20) - sc-19227 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ephrin-B2 (C-20): sc-19227. Western blot analysis of human recombinant ephrin-B2 fusion protein.

ephrin-B2 (H-83) - sc-15397 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ephrin-B2 (H-83): sc-15397. Immunoperoxidase staining of formalin fixed, paraffin-embedded human vulva/anal skin tissue showing cytoplasmic staining of surface epithelial cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

ephrin-B2 (P-20) - sc-1010 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ephrin-B2 (P-20): sc-1010. Western blot analysis of human recombinant ephrin-B2 fusion protein.

Anti-Ephrin B2 (phospho Y316) antibody - ab119323 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ephrin B2 (phospho Y316) antibody (ab119323) at 1/500 dilutionLane 1 : HT29 cell lysateLane 2 : HT29 cells, treated with UV and lysed

Anti-Ephrin B2 antibody - ab131536 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Ephrin B2 antibody (ab131536) at 1/500 dilution + HT29 cell extract

Anti-Ephrin B2 antibody - ab75868 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ephrin B2 antibody (ab75868) at 1/500 dilutionLane 1 : HUVEC cells, untreated with immunising peptideLane 2 : HUVEC cells, treated with EGFLane 3 : HUVEC cells, treated with Insulin

Anti-Ephrin B2 antibody - ab96264 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ephrin B2 antibody (ab96264) at 1 µg/mlLane 1 : Lung (Human) Tissue LysateLane 2 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Ephrin B2 antibody [EPR10072(B)] - ab150411 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10072(B)
All lanes : Anti-Ephrin B2 antibody [EPR10072(B)] (ab150411) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : Human fetal lung lysateLane 3 : 293T lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Ephrin B2 antibody [EPR10072(B)] (HRP) - ab201512 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10072(B)
All lanes : Anti-Ephrin B2 antibody [EPR10072(B)] (HRP) (ab201512) at 1/5000 dilutionLane 1 : Kidney (Human) Tissue Lysate - adult normal tissueLane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-Ephrin B2 antibody [PA3491843] - ab180837 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone PA3491843
Anti-Ephrin B2 antibody [PA3491843] (ab180837) at 5 µg/ml + COLO 205 cell lysate at 20 µgSecondaryHRP labeled Goat anti Mouse IgG at 1/4000 dilutiondeveloped using the ECL technique

Anti-EFNB2 / Ephrin B2 Antibody (phospho-Tyr316) - LS-C190760 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody - LS-C128759 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody - LS-C128758 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (phospho-Tyr330) - LS-C190761 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa164-194, AP) - LS-C213673 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa164-194, Biotin) - LS-C213675 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa164-194, APC) - LS-C213674 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa164-194, Azide-free, HRP) - LS-C213677 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa164-194, FITC) - LS-C213676 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa164-194, PE) - LS-C213678 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa164-194) - LS-C321036 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa62-74) - LS-C139620 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
EFNB2 antibody (0.1 ug/ml) staining of Rat Lung lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-EFNB2 / Ephrin B2 Antibody - LS-C341201 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EFNB2 / Ephrin B2 Antibody (aa42-333) - LS-C314976 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant EFNB2 / Ephrin B2.
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