| Name | sRANK Receptor, Human, Recombinant |
|---|---|
| Supplier | ARP American Research Products |
| Catalog | 28-10284 |
| Category | Protein |
| Prices | $99.00, $100.00, $199.00 |
| Sizes | 20 µg, 1 mg, 100 µg |
| Species Reactivities | Mouse |
| Nature | Recombinant |
| Source | E. Coli |
| Purity | 98% |
| Bioactivity | Determined by its ability to inhibit sRANKL induced NFkappaB in RAW264.7 cells in the absence of any cross-linking. The expected ED50 for this effect in the presence of 15ng/ml of recombinant sRANKL, is 30-50 ng/ml. |
| Endotoxin | Endotoxin level is <0.1 ng/ug of protein (<1EU/ug). |
| Gene | Tnfrsf11a |
| Sequence | MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK |
| Description | RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover |
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