Recombinant Mouse RANK/TNFRSF11A Fc Chimera Protein, CF

• Supplier: R&D Systems
• Catalog: 692-RK
• Category: Protein
• Prices: $345.00
• Sizes: 100 µg
• Species Reactivities: Mouse
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Met Mouse RANK (Gln30 - Pro213) Accession # O35305.1 IEGRDID Human IgG 1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its ability to inhibit TRANCE-induced osteoclast differentiation of mouse splenocytes. The ED 50 for this effect is 0.05‑0.15 µg/mL in the presence of 10 ng/mL of rmTRANCE.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: O35305.1
• Gene: Tnfrsf11a
• Sequence: Met

Product References

Epidermal growth factor receptor (EGFR) signaling is a key mediator of - Epidermal growth factor receptor (EGFR) signaling is a key mediator of

Aupperlee MD, Zhao Y, Tan YS, Leipprandt JR, Bennett J, Haslam SZ, Schwartz RC. Endocrinology. 2014 Jun;155(6):2301-13.

OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain - OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain

Shimamura M, Nakagami H, Osako MK, Kurinami H, Koriyama H, Zhengda P, Tomioka H, Tenma A, Wakayama K, Morishita R. Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8191-6. doi:

Osteoprotegerin reduces the serum level of receptor activator of NF-kappaB ligand - Osteoprotegerin reduces the serum level of receptor activator of NF-kappaB ligand

Nakamichi Y, Udagawa N, Kobayashi Y, Nakamura M, Yamamoto Y, Yamashita T, Mizoguchi T, Sato M, Mogi M, Penninger JM, Takahashi N. J Immunol. 2007 Jan 1;178(1):192-200.