GBA3

Gene Symbol GBA3
Entrez Gene 57733
Alt Symbol CBG, CBGL1, GLUC, KLRP
Species Human
Gene Type protein-coding
Description glucosidase, beta, acid 3 (gene/pseudogene)
Other Description cytosolic beta-glucosidase|cytosolic beta-glucosidase-like protein 1|glucosidase, beta, acid 3 (cytosolic)|klotho-related protein
Swissprots Q9H3T4 Q9H4C6 Q3MIH4 Q9H227 Q32LY7 Q8NHT8 Q53GG8 Q6NSF4
Accessions EAW92802 EAW92803 Q9H227 AB017913 BAB18741 AF317840 AAG39217 AF323990 AAL37305 AJ278964 CAC08178 AK222963 BAD96683 AK292746 BAF85435 AK298377 BAH12772 AK313189 BAG36006 BC029362 AAH29362 BC070188 AAH70188 BC101829 AAI01830 BC109377 AAI09378 BC136264 AAI36265 BP383134 CB163648 NM_001128432 NP_001121904 NM_001277225 NP_001264154 NM_020973 NP_066024 NR_102355 NR_102356 NR_102357
Function Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. {ECO:0000269|PubMed:11784319, ECO:0000269|PubMed:12594539, ECO:0000269|PubMed:17595169}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:12594539, ECO:0000269|PubMed:17595169}.
Tissue Specificity Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas. {ECO:0000269|PubMed:11043382, ECO:0000269|PubMed:12594539}.
Top Pathways Cyanoamino acid metabolism, Starch and sucrose metabolism

GBA3-Over-expression-Lysate - LY15797a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag GBA3 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GBA3 gene‘

GBA3 293T Cell Transient Overexpression Lysate(Denatured) - H00057733-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

GBA3 293 Cell Lysate - 402451 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Cytosolic beta-Glucosidase/GBA3 Overexpression Lysate (Denatured) - H00057733-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: GBA3 transfected lysate (17.93 KDa) Lane 2: Non-transfected lysate.

Cytosolic beta-Glucosidase/GBA3 Overexpression Lysate (Native) - NBL1-10992 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: GBA3 Overexpression Lysate (Adult Normal) [NBL1-10992] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GBA3.

GBA3 Over-expression Lysate Product - GWB-12EAFF from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Human GBA3 / CBGL1 Insect Cell Lysate (WB positive control) - 11593-H08BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human GBA3 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb174969 from Biorbyt

Category Cell Lysate
Prices $604.00
Sizes 300 μg
Species Human

Panoply™ Human GBA3 Knockdown Stable Cell Line - CSC-DC006137 from Creative biogene

Category Cell Line
Species Human
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