GBA3

Gene Symbol GBA3
Entrez Gene 57733
Alt Symbol CBG, CBGL1, GLUC, KLRP
Species Human
Gene Type protein-coding
Description glucosidase, beta, acid 3 (gene/pseudogene)
Other Description cytosolic beta-glucosidase|cytosolic beta-glucosidase-like protein 1|glucosidase, beta, acid 3 (cytosolic)|klotho-related protein
Swissprots Q9H3T4 Q9H4C6 Q3MIH4 Q9H227 Q32LY7 Q8NHT8 Q53GG8 Q6NSF4
Accessions EAW92802 EAW92803 Q9H227 AB017913 BAB18741 AF317840 AAG39217 AF323990 AAL37305 AJ278964 CAC08178 AK222963 BAD96683 AK292746 BAF85435 AK298377 BAH12772 AK313189 BAG36006 BC029362 AAH29362 BC070188 AAH70188 BC101829 AAI01830 BC109377 AAI09378 BC136264 AAI36265 BP383134 CB163648 NM_001128432 NP_001121904 NM_001277225 NP_001264154 NM_020973 NP_066024 NR_102355 NR_102356 NR_102357
Function Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. {ECO:0000269|PubMed:11784319, ECO:0000269|PubMed:12594539, ECO:0000269|PubMed:17595169}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:12594539, ECO:0000269|PubMed:17595169}.
Tissue Specificity Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas. {ECO:0000269|PubMed:11043382, ECO:0000269|PubMed:12594539}.
Top Pathways Cyanoamino acid metabolism, Starch and sucrose metabolism

CBG CRISPR/Cas9 KO Plasmid (h) - sc-406575 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CBG HDR Plasmid (h) - sc-406575-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CBG Double Nickase Plasmid (h) - sc-406575-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CBG Double Nickase Plasmid (h2) - sc-406575-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CBG CRISPR Activation Plasmid (h) - sc-406575-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CBG CRISPR Activation Plasmid (h2) - sc-406575-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CBG Lentiviral Activation Particles (h) - sc-406575-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CBG Lentiviral Activation Particles (h2) - sc-406575-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CBG siRNA (h) - sc-105182 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CBG shRNA Plasmid (h) - sc-105182-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CBG shRNA (h) Lentiviral Particles - sc-105182-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytosolic beta-Glucosidase/GBA3 RNAi - H00057733-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU039431 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9163 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9163 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05752 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05752

GBA3 siRNA (Human) - CRJ1669 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GBA3 - MBS8238782 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GBA3 (NM_020973.3) - SHH299730 from Creative biogene

Category siRNA
Species Reactivities Human

Human GBA3 siRNA - orb272170 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GBA3 shRNA Plasmid (Human) - CHJ1669 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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