IL6

Gene Symbol	IL6
Entrez Gene	3569
Alt Symbol	BSF2, HGF, HSF, IFNB2, IL-6
Species	Human
Gene Type	protein-coding
Description	interleukin 6
Other Description	B-cell differentiation factor|B-cell stimulatory factor 2|BSF-2|CDF|CTL differentiation factor|IFN-beta-2|hybridoma growth factor|interferon beta-2|interferon, beta 2|interleukin BSF-2|interleukin-6
Swissprots	P05231 Q9UCU2 Q9UCU3 Q9UCU4
Accessions	AAC05673 AAK48987 AAN75009 AAS07539 AFF18412 CAA27990 CAA68278 CAL23031 CCA63961 EAL24265 EAW93756 EAW93757 EAW93758 P05231 A09363 CAA00839 AA721478 AK298013 BAG60317 AK298077 BAG60365 AK301141 BAG62733 BC015511 AAH15511 BT019748 AAV38553 BT019749 AAV38554 CR450296 CAG29292 DQ891463 ABM82389 DQ894639 ABM85565 M14584 AAA52728 M18403 AAA52729 M29150 AAA59154 M54894 AAC41704 S56892 AAD13886 X04403 CAA27991 X04430 CAA28026 X04602 CAA28268 XM_005249745 XP_005249802 XM_011515390 XP_011513692 XM_011515391 XP_011513693 NM_000600 NP_000591
Function	Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Subcellular Location	Secreted.
Top Pathways	Non-alcoholic fatty liver disease (NAFLD), Legionellosis, TNF signaling pathway, Herpes simplex infection, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active cow IL6 full length protein - ab87933 from Abcam Category Protein Prices $257.00 Sizes 25 µg Source Yeast Species Bovine

Active horse IL6 full length protein - ab87934 from Abcam Category Protein Prices $315.00 Sizes 25 µg Source Yeast Species Horse

Active human IL6 full length protein - ab119444 from Abcam Category Protein Prices $315.00 Sizes 5 µg Source E. coli Species Human

Active human IL6 full length protein - ab151943 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Human

Active human IL6 full length protein - ab194176 from Abcam Category Protein Prices $199.00 Sizes 2 µg Source Mammalian Species Human

Active human IL6 full length protein - ab9627 from Abcam Category Protein Prices $257.00 Sizes 20 µg Source E. coli Species Human

Active human IL6 full length protein - ab198571 from Abcam Category Protein Prices $300.00 Sizes 20 µg Source E. coli Species Human

Active human IL6 full length protein - ab73197 from Abcam Category Protein Prices $200.00 Sizes 20 µg Source E. coli Species Human

Active mouse IL6 full length protein - ab198572 from Abcam Category Protein Prices $300.00 Sizes 10 µg Source E. coli Species Mouse

Active mouse IL6 full length protein - ab201439 from Abcam Category Protein Prices $101.00 Sizes 2 µg Source E. coli Species Mouse

Active mouse IL6 full length protein - ab9731 from Abcam Category Protein Prices $110.00, $257.00 Sizes 2 µg, 10 µg Source E. coli Species Mouse

Active mouse IL6 full length protein - ab191620 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Mouse

Active mouse IL6 full length protein - ab73199 from Abcam Category Protein Prices $148.00 Sizes 10 µg Source E. coli Species Mouse

Active rat IL6 full length protein - ab9771 from Abcam Category Protein Prices $257.00 Sizes 10 µg Source E. coli Species Rat

Active rat IL6 full length protein - ab179486 from Abcam Category Protein Prices $202.00 Sizes 10 µg Source E. coli Species Rat

Active rat IL6 full length protein - ab191631 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Rat

Active rat IL6 full length protein - ab73200 from Abcam Category Protein Prices $200.00 Sizes 10 µg Source E. coli Species Rat

Active rhesus monkey IL6 full length protein - ab200291 from Abcam Category Protein Prices $101.00 Sizes 2 µg Source E. coli Species Monkey

Cat IL6 full length protein - ab117233 from Abcam Category Protein Prices $345.00 Sizes 25 µg Source Yeast Species Cat

Chicken IL6 full length protein - ab107958 from Abcam Category Protein Prices $252.00 Sizes 25 µg Source Yeast Species Chicken

Dog IL6 full length protein - ab88007 from Abcam Category Protein Prices $252.00 Sizes 25 µg Source Yeast Species Dog

Human IL6 full length protein - ab101044 from Abcam Category Protein Source E. coli Species Human

Human IL6 full length protein - ab53327 from Abcam Category Protein Source E. coli Species Human

Human IL6 peptide - ab103272 from Abcam Category Peptide

IL6 peptide - ab94382 from Abcam Category Peptide

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