IL6

Gene Symbol IL6
Entrez Gene 3569
Alt Symbol BSF2, HGF, HSF, IFNB2, IL-6
Species Human
Gene Type protein-coding
Description interleukin 6
Other Description B-cell differentiation factor|B-cell stimulatory factor 2|BSF-2|CDF|CTL differentiation factor|IFN-beta-2|hybridoma growth factor|interferon beta-2|interferon, beta 2|interleukin BSF-2|interleukin-6
Swissprots P05231 Q9UCU2 Q9UCU3 Q9UCU4
Accessions AAC05673 AAK48987 AAN75009 AAS07539 AFF18412 CAA27990 CAA68278 CAL23031 CCA63961 EAL24265 EAW93756 EAW93757 EAW93758 P05231 A09363 CAA00839 AA721478 AK298013 BAG60317 AK298077 BAG60365 AK301141 BAG62733 BC015511 AAH15511 BT019748 AAV38553 BT019749 AAV38554 CR450296 CAG29292 DQ891463 ABM82389 DQ894639 ABM85565 M14584 AAA52728 M18403 AAA52729 M29150 AAA59154 M54894 AAC41704 S56892 AAD13886 X04403 CAA27991 X04430 CAA28026 X04602 CAA28268 XM_005249745 XP_005249802 XM_011515390 XP_011513692 XM_011515391 XP_011513693 NM_000600 NP_000591
Function Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Subcellular Location Secreted.
Top Pathways Non-alcoholic fatty liver disease (NAFLD), Legionellosis, TNF signaling pathway, Herpes simplex infection, PI3K-Akt signaling pathway

IL-6 CRISPR/Cas9 KO Plasmid (h) - sc-400390 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6 HDR Plasmid (h) - sc-400390-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6 Double Nickase Plasmid (h) - sc-400390-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6 Double Nickase Plasmid (h2) - sc-400390-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6 CRISPR Activation Plasmid (h) - sc-400390-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6 CRISPR Activation Plasmid (h2) - sc-400390-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6 Lentiviral Activation Particles (h) - sc-400390-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6 Lentiviral Activation Particles (h2) - sc-400390-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6 siRNA (h) - sc-39627 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-6 shRNA Plasmid (h) - sc-39627-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-6 shRNA (h) Lentiviral Particles - sc-39627-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-6 RNAi - H00003569-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU021251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU046621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1757 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1757 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00019 from Sigma-Aldrich

Category miRNA
Prices $522.00
Sizes hutr00019

IL6 siRNA (Human) - CRH2386 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL6 - MBS8216778 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IL6 (NM_000600.3) - SHH319045 from Creative biogene

Category siRNA
Species Reactivities Human

IL6 shRNA Plasmid (Human) - CHH2386 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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