BAD

Gene Symbol	BAD
Entrez Gene	572
Alt Symbol	BBC2, BCL2L8
Species	Human
Gene Type	protein-coding
Description	BCL2-associated agonist of cell death
Other Description	BCL-X/BCL-2 binding protein|BCL2-antagonist of cell death protein|BCL2-binding component 6|BCL2-binding protein|bcl-2-binding component 6|bcl-2-like protein 8|bcl-XL/Bcl-2-associated death promoter|bcl2 antagonist of cell death|bcl2-L-8|bcl2-associated agonist of cell death
Swissprots	O14803 Q6FH21 Q92934
Accessions	EAW74233 EAW74234 EAW74235 EAW74236 Q92934 AB451254 BAG70068 AB451378 BAG70192 AF021792 AAB72092 AF031523 AAB88124 AK023420 AK291863 BAF84552 AK303051 BAG64171 AK309150 AW014069 BC001901 AAH01901 BC095431 AAH95431 BE255791 BG435829 BG748336 BT006678 AAP35324 CR541935 CAG46733 CR541959 CAG46757 DQ895784 ABM86710 EU176363 ABW03814 U66879 AAB36516 NM_004322 NP_004313 NM_032989 NP_116784
Function	Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. {ECO:0000250}.
Subcellular Location	Mitochondrion outer membrane. Cytoplasm {ECO:0000250|UniProtKB:Q61337}. Note=Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm. {ECO:0000250|UniProtKB:Q61337}.
Tissue Specificity	Expressed in a wide variety of tissues.
Top Pathways	Apoptosis, Hepatitis C, cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BBC2 Gene - orb90642 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

BAD - MBS1276583 from MyBioSource Species Human Accession BC001901

Human Bad Gene ORF cDNA clone in cloning vector - HG10020-M from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10020-NF from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10020-CF from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10020-NM from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10020-CM from Sino Biological Species Human

Human BAD transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10020-M-F from Sino Biological Species Human Accession NM_004322.2

Human Bad Gene ORF cDNA clone expression plasmid, N-His tag - HG10020-NH from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10020-ACR from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10020-ANR from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10020-ANG from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, C-HA tag - HG10020-CY from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, C-His tag - HG10020-CH from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid - HG10020-UT from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, N-HA tag - HG10020-NY from Sino Biological Species Human

Human Bad Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10020-ACG from Sino Biological Species Human

Bad - CL01203H01 from Elabscience Species Human Accession NM_004322.3

Bad - CL01203H02 from Elabscience Species Human Accession NM_032989.2

Human BAD ORF Clone (BC001901) - CDCS411730 from Creative biogene Species Human Accession Q92934

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