KDSR

Gene Symbol KDSR
Entrez Gene 2531
Alt Symbol DHSR, FVT1, SDR35C1
Species Human
Gene Type protein-coding
Description 3-ketodihydrosphingosine reductase
Other Description 3-dehydrosphinganine reductase|FVT-1|KDS reductase|follicular lymphoma variant translocation 1|follicular variant translocation protein 1|short chain dehydrogenase/reductase family 35C member 1|short chain dehydrogenase/reductase family 35C, member 1
Swissprots B2R5Y1 Q06136 B4DMX0
Accessions EAW63140 EAW63141 Q06136 AF086045 AK025120 AK093874 AK126679 AK297670 BAG60032 AK312360 BAG35278 BC008797 AAH08797 BI458411 BT006782 AAP35428 X63657 CAA45197 XM_005266677 XP_005266734 XM_006722433 XP_006722496 NM_002035 NP_002026
Function Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:15328338}; Multi-pass membrane protein {ECO:0000269|PubMed:15328338}.
Tissue Specificity Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.
Top Pathways Sphingolipid metabolism

FVT1 CRISPR/Cas9 KO Plasmid (h) - sc-409132 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FVT1 HDR Plasmid (h) - sc-409132-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FVT1 Double Nickase Plasmid (h) - sc-409132-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FVT1 Double Nickase Plasmid (h2) - sc-409132-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FVT1 CRISPR Activation Plasmid (h) - sc-409132-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FVT1 CRISPR Activation Plasmid (h2) - sc-409132-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FVT1 Lentiviral Activation Particles (h) - sc-409132-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FVT1 Lentiviral Activation Particles (h2) - sc-409132-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FVT1 siRNA (h) - sc-75069 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FVT1 shRNA Plasmid (h) - sc-75069-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FVT1 shRNA (h) Lentiviral Particles - sc-75069-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FVT1 RNAi - H00002531-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU086021 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11040 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11040 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KDSR siRNA (Human) - CRH1676 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KDSR (NM_002035.2) - SHH324303 from Creative biogene

Category siRNA
Species Reactivities Human

KDSR shRNA Plasmid (Human) - CHH1676 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KDSR miRNA 3'UTR clone - MiUTR1H-03884 from Creative biogene

Species Reactivities Human
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