CFL2

Gene Symbol CFL2
Entrez Gene 1073
Alt Symbol NEM7
Species Human
Gene Type protein-coding
Description cofilin 2 (muscle)
Other Description cofilin, muscle isoform|cofilin-2|nemaline myopathy type 7
Swissprots Q9Y281 G3V5P4
Accessions AAF64498 AAF97934 EAW65908 EAW65910 EAW65911 EAW65912 Q9Y281 AF087867 AAM10495 AF134802 AAD31280 AF134803 AAD31281 AI754134 AK314157 BAG36842 AL117457 AL599958 BC011444 AAH11444 BC022364 AAH22364 BC022876 AAH22876 BC025683 CB992605 DA298739 DA897112 DB378917 EU832642 ACE87733 EU832719 ACE87051 XM_011536363 XP_011534665 NM_001243645 NP_001230574 NM_021914 NP_068733 NM_138638 NP_619579 NR_028130 NR_028131
Function Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity). {ECO:0000250}.
Subcellular Location Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Tissue Specificity Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Top Pathways Axon guidance, Fc gamma R-mediated phagocytosis, Pertussis, Regulation of actin cytoskeleton

Cofilin 2 (D-5) - sc-166958 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cofilin 2 (D-5): sc-166958. Western blot analysis of Cofilin 2 expression in Sol8 whole cell lysate (A) and rat skeletal muscle tissue extract (B).

Cofilin 2 (H-19) - sc-32160 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cofilin 2 (H-19): sc-32160. Western blot analysis of Cofilin 2 expression in non-transfected: sc-117752 (A) and mouse Cofilin 2 transfected: sc-119353 (B) 293T whole cell lysates.

Anti-Cofilin 2 (phospho S3) antibody - ab14134 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Cofilin 2 antibody - ab96678 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Cofilin 2 antibody (ab96678) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-Cofilin 2 antibody - ab54536 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Cofilin 2 antibody (ab54536) used in immunohistochemistry at 8ug/ml on formalin fixed and paraffin embedded human skeletal muscle.

Anti-Cofilin 2 antibody - ab14133 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (aa92-166) - LS-C185345 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded gastric CA using Cofilin 2 antibody at 1:100 dilution.

Anti-CFL2 / Cofilin 2 Antibody (C-Terminus) IHC-plus™ - LS-B9191 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-CFL2 / Cofilin 2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CFL2 / Cofilin 2 Antibody (aa130-144) - LS-C344258 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent image of HeLa cells stained with CFL2 Antibody. Antibody was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor 555 conjugated with Phalloidin (red).

Anti-CFL2 / Cofilin 2 Antibody (aa136-152) - LS-C22265 from LifeSpan Bioscience

Prices $560.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (phospho-Ser3) - LS-C22266 from LifeSpan Bioscience

Prices $560.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (aa24-54, AP) - LS-C254679 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (aa24-54, APC) - LS-C254680 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (aa24-54, Azide-free, HRP) - LS-C254682 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (aa24-54, FITC) - LS-C254683 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (aa24-54, Biotin) - LS-C254681 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (aa24-54, PE) - LS-C254684 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (C-Terminus) - LS-C146390 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CFL2 antibody LS-C146390 Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml.

Anti-CFL2 / Cofilin 2 Antibody (aa57-167, Azide-free) - LS-C327092 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CFL2 / Cofilin 2 Antibody (aa24-54) - LS-C329388 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CFL2 / Cofilin 2 Antibody (aa1-166) - LS-C186322 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa using Cofilin 2 (muscle) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2500.

Anti-CFL2 / Cofilin 2 Antibody (aa1-156) - LS-C293407 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant CFL2 / Cofilin 2.

Anti-CFL2 / Cofilin 2 Antibody (clone 6G9) - LS-C133115 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6G9
Immunoperoxidase of monoclonal antibody to CFL2 on formalin-fixed paraffin-embedded human skeletal muscle. [antibody concentration 8 ug/ml]

Anti-CFL2 / Cofilin 2 Antibody (aa24-54) - LS-C168707 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CFL2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human rectum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Cofilin 2 Antibody (6G9) - H00001073-M03 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6G9
Western Blot: Cofilin 2 Antibody (6G9) [H00001073-M03] - Western Blot analysis of CFL2 expression in HeLa ( Cat # L013V1 ).
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