CFL2

Gene Symbol CFL2
Entrez Gene 1073
Alt Symbol NEM7
Species Human
Gene Type protein-coding
Description cofilin 2 (muscle)
Other Description cofilin, muscle isoform|cofilin-2|nemaline myopathy type 7
Swissprots Q9Y281 G3V5P4
Accessions AAF64498 AAF97934 EAW65908 EAW65910 EAW65911 EAW65912 Q9Y281 AF087867 AAM10495 AF134802 AAD31280 AF134803 AAD31281 AI754134 AK314157 BAG36842 AL117457 AL599958 BC011444 AAH11444 BC022364 AAH22364 BC022876 AAH22876 BC025683 CB992605 DA298739 DA897112 DB378917 EU832642 ACE87733 EU832719 ACE87051 XM_011536363 XP_011534665 NM_001243645 NP_001230574 NM_021914 NP_068733 NM_138638 NP_619579 NR_028130 NR_028131
Function Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity). {ECO:0000250}.
Subcellular Location Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Tissue Specificity Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Top Pathways Axon guidance, Fc gamma R-mediated phagocytosis, Pertussis, Regulation of actin cytoskeleton

CFL2-Over-expression-Lysate - LY12377a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CFL2 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CFL2 gene

CFL2 293 Cell Lysate - 402917 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg
Tissue Muscle

Cofilin 2 Overexpression Lysate (Native) - NBL1-09127 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Cofilin 2 Overexpression Lysate (Adult Normal) [NBL1-09127] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cofilin 2.

Cofilin 2 Overexpression Lysate (Native) - NBP2-06506 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Cofilin 2 Overexpression Lysate (Adult Normal) [NBP2-06506] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cofilin 2.

CFL2 Over-expression Lysate Product - GWB-490073 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Cofilin 2 Overexpression Lysate (Native) - NBP2-11264 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Cofilin 2 Overexpression Lysate (Adult Normal) [NBP2-11264] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cofilin 2.

Panoply™ Human CFL2 Knockdown Stable Cell Line - CSC-DC003040 from Creative biogene

Category Cell Line
Species Human
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