EXOSC10

Gene Symbol EXOSC10
Entrez Gene 5394
Alt Symbol PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
Species Human
Gene Type protein-coding
Description exosome component 10
Other Description P100 polymyositis-scleroderma overlap syndrome-associated autoantigen|autoantigen PM-SCL|polymyositis/scleroderma autoantigen 100 kDa|polymyositis/scleroderma autoantigen 2
Swissprots Q01780 B1AKQ1 Q15158 B1AKQ0
Accessions AAF73199 CAC15569 CAV30720 CAV30721 CCQ43005 EAW71677 EAW71678 EAW71679 Q01780 AB209236 BAD92473 AK093955 AK123365 AK294058 BAG57405 AK296559 BAG59180 AK308778 BC008460 BC009908 AAH09908 BC028687 BC039901 AAH39901 BC073788 AAH73788 CA307576 DA505395 EU832630 ACE87721 EU832705 ACE87037 L01457 AAB59352 X66113 CAA46904 XM_005263475 XP_005263532 XM_005263476 XP_005263533 XM_011541595 XP_011539897 NM_001001998 NP_001001998 NM_002685 NP_002676
Function Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pat
Subcellular Location Cytoplasm. Nucleus, nucleolus. Nucleus. Note=Strongly enriched in the nucleolus and a small amount has been found in cytoplasm supporting the existence of a nucleolar RNA exosome complex form.
Top Pathways RNA degradation

Anti exosome component 10 (EXOSC10) antibody, Human, ELISA kit - CSB-EQ027694HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Exosome component 10 (EXOSC10), Human, ELISA Kit - CSB-EL007889HU from ARP American Research Products

Category ELISA Kit
Prices $615.00, $815.00
Sizes 48 t, 96 t

Human Anti-PM-Scl ELISA Kit - HP0698 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Anserine PM-Scl/PM-1 ELISA Kit - AP0698 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

anti exosome component 10 (EXOSC10) antibody, ELISA Kit - MBS706521 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

exosome component 10, ELISA Kit - MBS9316926 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human anti exosome component 10(EXOSC10) antibody ELISA kit - CSB-EQ027694HU from Cusabio

Category ELISA Kit
Sensitivity Request Information
Range Request Information

Human anti exosome component 10(EXOSC10) antibody ELISA Kit - EKC32623 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,287.50
Sizes 96 t, 5x96t, 10x96t
Sensitivity Request Information
Range Request Information

Human EXOSC10 ELISA Kit - E013842 from Biobool

Category ELISA Kit

Human PM Scl ELISA Kit - E030147 from Biobool

Category ELISA Kit

Human PM-SCL ELISA Kit - E030148 from Biobool

Category ELISA Kit

Human PM-Scl / PM-1 ELISA Kit - E030149 from Biobool

Category ELISA Kit

Human Anti-PM-Scl ELISA Kit - EHP0698 from ABclonal

Category ELISA Kit
Prices $495.00
Sizes 96 t
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