DGAT1

Gene Symbol DGAT1
Entrez Gene 8694
Alt Symbol ARAT, ARGP1, DGAT, DIAR7
Species Human
Gene Type protein-coding
Description diacylglycerol O-acyltransferase 1
Other Description ACAT related gene product 1|acyl coenzyme A:cholesterol acyltransferase related gene 1|acyl-CoA retinol O-fatty-acyltransferase|acyl-CoA:diacylglycerol acyltransferase|diglyceride acyltransferase
Swissprots B2RWQ2 Q96BB8 O75907 D3DWL6
Accessions EAW82127 EAW82128 EAW82129 EAW82130 O75907 AB057815 BAC66170 AF059202 AAC63997 BC006263 AAH06263 BC015762 AAH15762 BC023565 AAH23565 BC106084 AAI06085 BC150649 AAI50650 BI907285 CK300256 DQ892286 ABM83212 DQ895486 ABM86412 HY016503 XM_011517356 XP_011515658 NM_012079 NP_036211
Function Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. {ECO:0000269|PubMed:16214399, ECO:0000269|PubMed:9756920}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Fat digestion and absorption, Glycerolipid metabolism, Retinol metabolism

DGAT1 (A-5) - sc-271934 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DGAT1 (A-5): sc-271934. Western blot analysis of DGAT1 expression in non-transfected: sc-117752 (A) and human DGAT1 transfected: sc-171964 (B) 293T whole cell lysates.

DGAT1 (H-255) - sc-32861 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DGAT1 (H-255): sc-32861. Western blot analysis of DGAT1 expression in non-transfected 293T: sc-117752 (A), mouse DGAT1 transfected 293T: sc-119756 (B) and HeLa (C) whole cell lysates.

DGAT1 (G-6) - sc-271935 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DGAT1 (G-6): sc-271935. Western blot analysis of DGAT1 expression in non-transfected: sc-117752 (A) and human DGAT1 transfected: sc-171964 (B) 293T whole cell lysates.

DGAT1 (N-20) - sc-26170 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DGAT1 (N-20): sc-26170. Immunofluorescence staining of methanol-fixed Jurkat cells showing membrane and cytoplasmic localization.

Anti-DGAT1 antibody [EPR13430-4] - N-terminal - ab181180 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13430-4
Anti-DGAT1 antibody [EPR13430-4] - N-terminal (ab181180) at 1/50000 dilution + HeLa cell lysate at 10 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-DGAT1 Antibody (Internal, Biotin) - LS-C141387 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DGAT1 Antibody (Internal, DY650) - LS-C141388 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DGAT1 Antibody (Internal, DY488) - LS-C141389 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DGAT1 Antibody (Internal, DY550) - LS-C141391 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DGAT1 Antibody (Internal, HRP) - LS-C141390 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DGAT1 Antibody (aa200-300) - LS-C49135 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of DGAT1 in HepG2 lysate.

Anti-DGAT1 Antibody (aa308) - LS-C190193 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DGAT1 Antibody (aa180-427, FITC) - LS-C301911 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DGAT1 Antibody (aa180-427, Biotin) - LS-C297837 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DGAT1 Antibody - LS-C146985 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of DGAT1 / DGAT antibody LS-C146985.

Anti-DGAT1 Antibody (aa78-127) - LS-C186729 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Mouse Heart. Dgat1 antibody dilution 1.0 ug/ml.

Anti-DGAT1 Antibody (aa180-427) - LS-C294118 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant DGAT1 / DGAT.

Anti-DGAT1 Antibody - LS-C334965 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse heart tissue, using DGAT1 antibody.

Anti-DGAT1 Antibody (aa217-229) IHC-plus™ - LS-B5914 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-DGAT1 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5914 concentration 3.75 ug/ml.

Anti-DGAT1 Antibody (aa67-79) IHC-plus™ - LS-B9542 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-DGAT1 / DGAT antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9542 concentration 5 ug/ml.

DGAT1 Antibody - NB110-41487 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DGAT1 Antibody [NB110-41487] - Detection of DGAT1 in HepG2 lysate.

DGAT1 Antibody - NB100-57086 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: DGAT1 Antibody [NB100-57086] - Staining of Rat Duodenum lysate.

DGAT1 Antibody - NBP2-26215 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: DGAT1 Antibody [NBP2-26215] - Staining of Mouse Duodenum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

DGAT1 Antibody [FITC] - NB110-41487F from Novus Biologicals

Prices $309.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DGAT1 Antibody [DyLight 405] - NB110-41487V from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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