POLR3F

Gene Symbol	POLR3F
Entrez Gene	10621
Alt Symbol	RPC39, RPC6
Species	Human
Gene Type	protein-coding
Description	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
Other Description	DNA-directed RNA polymerase III subunit RPC6|RNA polymerase III C39 subunit|RNA polymerase III subunit C6
Swissprots	O15319 Q9H1D9 A8K4C7
Accessions	EAX10239 EAX10240 EAX10241 Q9H1D9 AK096684 AK223298 BAD97018 AK290892 BAF83581 AK314838 BC012588 AAH12588 BC016761 AAH16761 DA729767 DQ892695 ABM83621 DQ896169 ABM87168 N98418 U93869 AAB63677 XM_011529141 XP_011527443 XR_937031 NM_001282526 NP_001269455 NM_006466 NP_006457 NR_104209
Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. {ECO:0000269|PubMed:19609254, ECO:0000269|PubMed:19631370}.
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human POLR3F full length protein - ab139235 from Abcam Category Protein Source E. coli Species Human

POLR3F Antibody Blocking Peptide - LS-E17607 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLR3F Antibody Blocking Peptide - LS-E17606 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLR3F Antibody Blocking Peptide - LS-E30541 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

POLR3F Recombinant Protein - H00010621-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human POLR3F Protein - NBP2-23350 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

POLR3F Blocking Peptide - NBP1-76929PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Human POLR3F protein - orb169054 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

POLR3F Blocking Peptide - 33R-5647 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

POLR3F Blocking Peptide - 33R-5238 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

POLR3F protein (His tag) - 30R-2961 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

POLR3F Blocking Peptide - abx063691 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

POLR3F (1-316, His-tag) - AR50721PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

POLR3F (1-316, His-tag) - AR50721PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

POLR3F - H00010621-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

POLR3F - H00010621-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

POLR3F Control Peptide - AP30684CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

POLR3F, 1-316aa, Human, His tag, E.coli - 01-P1897 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

POLR3F Peptide - 4727P from ProSci Category Peptide Species Human

POLR3F fusion protein - Ag9188 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

POLR3F fusion protein - Ag8935 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

POLR3F Human - ENPS-657 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

Human POLR3F Recombinant Protein - GWB-PPAT59 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human POLR3F, His-tagged - POLR3F-7115H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human POLR3F, His-tagged - POLR3F-1851H from Creative Biomart Category Protein Source E.coli Species Human

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