| Gene Symbol |
Slc2a2
|
| Entrez Gene |
20526
|
| Alt Symbol |
AI266973, Glut-2, Glut2
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 2 (facilitated glucose transporter), member 2
|
| Other Description |
glucose transporter type 2, liver|liver-type glucose transporter|solute carrier family 2, facilitated glucose transporter member 2
|
| Swissprots |
Q9DBA7 P14246 Q3TNA5
|
| Accessions |
AAL49973 CAA55368 CBN59671 CBN63423 CBN65602 EDL34941 EDL34942 EDL34943 P14246 AI120520 AK005068 BAB23792 AK149532 AK165430 BAE38184 BC034675 AAH34675 S77926 AAB20847 X15684 CAA33719 X16986 CAA34855 NM_031197 NP_112474
|
| Function |
Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
In embryo, expressed in endoderm layer of yolk sac and liver primordium. {ECO:0000269|PubMed:1289053}.
|
| Top Pathways |
Type II diabetes mellitus, Maturity onset diabetes of the young, Carbohydrate digestion and absorption, Prolactin signaling pathway, Central carbon metabolism in cancer
|