Gene Symbol | Slc2a2 |
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Entrez Gene | 20526 |
Alt Symbol | AI266973, Glut-2, Glut2 |
Species | Mouse |
Gene Type | protein-coding |
Description | solute carrier family 2 (facilitated glucose transporter), member 2 |
Other Description | glucose transporter type 2, liver|liver-type glucose transporter|solute carrier family 2, facilitated glucose transporter member 2 |
Swissprots | Q9DBA7 P14246 Q3TNA5 |
Accessions | AAL49973 CAA55368 CBN59671 CBN63423 CBN65602 EDL34941 EDL34942 EDL34943 P14246 AI120520 AK005068 BAB23792 AK149532 AK165430 BAE38184 BC034675 AAH34675 S77926 AAB20847 X15684 CAA33719 X16986 CAA34855 NM_031197 NP_112474 |
Function | Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | In embryo, expressed in endoderm layer of yolk sac and liver primordium. {ECO:0000269|PubMed:1289053}. |
Top Pathways | Type II diabetes mellitus, Maturity onset diabetes of the young, Carbohydrate digestion and absorption, Prolactin signaling pathway, Central carbon metabolism in cancer |
Glut2 CRISPR/Cas9 KO Plasmid (m) - sc-422999 from Santa Cruz Biotechnology
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Glut2 HDR Plasmid (m) - sc-422999-HDR from Santa Cruz Biotechnology
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Glut2 Double Nickase Plasmid (m) - sc-422999-NIC from Santa Cruz Biotechnology
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Glut2 Double Nickase Plasmid (m2) - sc-422999-NIC-2 from Santa Cruz Biotechnology
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Glut2 CRISPR Activation Plasmid (m) - sc-422999-ACT from Santa Cruz Biotechnology
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Glut2 CRISPR Activation Plasmid (m2) - sc-422999-ACT-2 from Santa Cruz Biotechnology
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Glut2 Lentiviral Activation Particles (m) - sc-422999-LAC from Santa Cruz Biotechnology
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Glut2 Lentiviral Activation Particles (m2) - sc-422999-LAC-2 from Santa Cruz Biotechnology
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Glut2 siRNA (m) - sc-35496 from Santa Cruz Biotechnology
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Glut2 shRNA Plasmid (m) - sc-35496-SH from Santa Cruz Biotechnology
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Glut2 shRNA (m) Lentiviral Particles - sc-35496-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN41411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND41411 from Sigma-Aldrich
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SLC2A2 siRNA (Mouse) - CRM3776 from Cohesion Biosciences
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SLC2A2 - MBS8214865 from MyBioSource
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shRNA set against Mouse SLC2A2 (NM_031197.2) - SHH410256 from Creative biogene
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shRNA set against Mouse Slc2a2(NM_031197.2) - SHL005708 from Creative biogene
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SLC2A2 shRNA Plasmid (Mouse) - CHM3776 from Cohesion Biosciences
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SLC2A2 miRNA 3'UTR clone - MiUTR1M-10840 from Creative biogene
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