ZFHX3

Gene Symbol ZFHX3
Entrez Gene 463
Alt Symbol ATBF1, ATBT, ZNF927
Species Human
Gene Type protein-coding
Description zinc finger homeobox 3
Other Description AT motif-binding factor 1|AT-binding transcription factor 1|ZFH-3|alpha-fetoprotein enhancer binding protein|alpha-fetoprotein enhancer-binding protein|zinc finger homeobox protein 3|zinc finger homeodomain protein 3
Swissprots O15101 Q13719 D3DWS8 Q15911
Accessions AAC31674 AAC79153 AAR26475 EAW59168 EAW59169 EAW59170 Q15911 BC029653 AAH29653 BC043190 D10250 BAA01095 L32832 AAC14462 L32833 AAC37582 XM_005255957 XP_005256014 NM_001164766 NP_001158238 NM_006885 NP_008816
Function Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down- regulates the MUC5AC promoter in gastric cancer. {ECO:0000269|PubMed:11312261, ECO:0000269|PubMed:17330845}.
Subcellular Location Nucleus.
Tissue Specificity Not found in normal gastric mucosa but found in gastric carcinoma cells (at protein level). {ECO:0000269|PubMed:17330845}.
Top Pathways Signaling pathways regulating pluripotency of stem cells

ATBF1 (C-15) - sc-21044 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ATBF1 (G-13) - sc-21162 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ATBF1 (H-150) - sc-48807 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ATBF1-A (I-19) - sc-21160 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ATBF1-A (Q-20) - sc-21161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ATBF1 antibody - ab119909 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ATBF1 antibody (ab119909) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : MCF7 cell lysateLane 3 : A549 cell lysate

Anti-ATBF1 antibody - ab54853 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-ATBF1 antibody (ab54853) at 1/500 dilution + Recombinant tagged fragment of human ATBF1 at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/5000 dilutionObserved band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-ZFHX3 / ATBF1 Antibody (aa761-810) - LS-C119078 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using ZFHX3 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-ZFHX3 / ATBF1 Antibody (aa517-787) IHC-plus™ - LS-B10493 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ZFHX3 / ATBF1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10493 concentration 5 ug/ml.

Anti-ZFHX3 / ATBF1 Antibody - LS-C179898 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZFHX3 / ATBF1 Antibody (clone 3B1) - LS-C196706 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B1
Immunofluorescence of monoclonal antibody to ZFHX3 on HeLa cell . [antibody concentration 10 ug/ml]

Anti-ZFHX3 / ATBF1 Antibody - LS-C179897 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATBF1/ZFHX3 Antibody - AF7384 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
ATBF1/ZFHX3 was detected in immersion fixed MCF-7 human breast cancer cell line using Sheep Anti-Human ATBF1/ZFHX3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7384) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red, upper panel; Catalog # NL010) and counterstained with DAPI (blue, lower panel). Specific staining was localized to nuclei and cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

ATBF1/ZFHX3 Antibody - NBP2-34126 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ATBF1/ZFHX3 Antibody [NBP2-34126] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

ATBF1/ZFHX3 Antibody (3B1) - H00000463-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B1

ATBF1/ZFHX3 Antibody - H00000463-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

ATBF1 Polyclonal Antibody - bs-11805R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Paraformaldehyde-fixed, paraffin embedded rat kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes;  Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with ATBF1 Polyclonal Antibody, Unconjugated (bs-11805R) at 1:200 overnight at 4°C, followed by a conjugated secondary and DAB staining.

ATBF1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11805R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATBF1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11805R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATBF1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11805R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATBF1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11805R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATBF1 Polyclonal Antibody, Cy3 Conjugated - bs-11805R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATBF1 Polyclonal Antibody, Cy5 Conjugated - bs-11805R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATBF1 Polyclonal Antibody, Cy5.5 Conjugated - bs-11805R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATBF1 Polyclonal Antibody, Cy7 Conjugated - bs-11805R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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