HSPB1

Gene Symbol	HSPB1
Entrez Gene	3315
Alt Symbol	CMT2F, HEL-S-102, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27
Species	Human
Gene Type	protein-coding
Description	heat shock 27kDa protein 1
Other Description	28 kDa heat shock protein|HSP 27|epididymis secretory protein Li 102|estrogen-regulated 24 kDa protein|heat shock 27 kDa protein|heat shock 27kD protein 1|heat shock protein beta-1|stress-responsive protein 27
Swissprots	Q6FI47 Q96EI7 Q9UC35 Q96C20 B2R4N8 Q9UC36 Q9UC31 P04792 Q9UC34
Accessions	AAA62175 ABC88475 CDM22284 EAW71803 P04792 AB020027 BAB17232 AF086135 AK296890 BAG59449 AK311446 AK311894 BAG34835 AL050380 BC000510 AAH00510 BC012292 AAH12292 BC012768 AAH12768 BC014920 AAH14920 BC073768 AAH73768 BP231480 BT019888 AAV38691 CR407614 CAG28542 CR536489 CAG38728 DQ891304 ABM82230 DQ893349 ABM84275 DQ894489 ABM85415 DQ896669 ABM87668 FJ224323 ACI46015 S74571 AAB20722 U90906 AAB51056 X16477 CAA34498 X54079 CAA38016 NM_001540 NP_001531
Function	Involved in stress resistance and actin organization.
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Tissue Specificity	Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle. {ECO:0000269|PubMed:1560006}.
Top Pathways	VEGF signaling pathway, MAPK signaling pathway, Amoebiasis, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Hsp27 (phospho S15) peptide - ab41772 from Abcam Category Peptide Species Human

Human Hsp27 (phospho S82) full length protein - ab113185 from Abcam Category Protein Source E. coli Species Human

Human Hsp27 full length protein - ab48740 from Abcam Category Protein Source E. coli Species Human

Human Hsp27 full length protein - ab91578 from Abcam Category Protein Source E. coli Species Human

Human Hsp27 full length protein - ab92410 from Abcam Category Protein Source E. coli Species Human

Human Hsp27 full length protein - ab124305 from Abcam Category Protein Source E. coli Species Human

Human Hsp27 full length protein - ab73799 from Abcam Category Protein Source E. coli Species Human

Human Hsp27 peptide - ab39789 from Abcam Category Peptide Species Human

Human Hsp27 peptide - ab86942 from Abcam Category Peptide

Mouse Hsp27 full length protein - ab92457 from Abcam Category Protein Source E. coli Species Mouse

Mouse Hsp27 full length protein - ab92321 from Abcam Category Protein Source E. coli Species Mouse

HSPB1 / HSP27 Antibody Blocking Peptide - LS-E10510 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSPB1 / HSP27 Antibody Blocking Peptide - LS-E10572 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSPB1 / HSP27 Antibody Blocking Peptide - LS-E8755 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSPB1 / HSP27 Antibody Blocking Peptide - LS-E8757 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSPB1 / HSP27 Antibody Blocking Peptide - LS-E8758 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSPB1 / HSP27 Antibody Blocking Peptide - LS-E8756 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSPB1 / HSP27 Antibody Blocking Peptide - LS-E7354 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSP27 Recombinant Protein - H00003315-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HSP27 Partial Recombinant Protein - H00003315-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human HSP27 Protein - NBC1-18364 from Novus Biologicals Category Protein Prices $249.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human HSP27 Protein - NBP1-30308 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

HSP27 Recombinant Protein - P4148 from Novus Biologicals Category Protein Prices $669.00 Sizes 10 µg Species Human

Recombinant Human HSP27 Protein - NBP1-99566 from Novus Biologicals Category Protein Prices $275.00 Sizes 10 µg Source E. coli Species Human

Recombinant Human HSP27 Protein [DyLight 650] - NBC1-18364C from Novus Biologicals Category Protein Prices $329.00 Sizes 100 µg Source E.coli Species Human

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