PPP2R5B

Gene Symbol PPP2R5B
Entrez Gene 5526
Alt Symbol B56B, PR61B
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit B', beta
Other Description PP2A B subunit isoform B'-beta|PP2A B subunit isoform B56-beta|PP2A B subunit isoform PR61-beta|PP2A B subunit isoform R5-beta|protein phosphatase 2, regulatory subunit B', beta isoform|serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform|serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Swissprots Q13853 Q15173
Accessions EAW74324 EAW74325 Q15173 AK092730 BC045619 AAH45619 BE883575 BM665417 EU446998 ABZ92527 L42374 AAC37602 XM_006718607 XP_006718670 XM_011545132 XP_011543434 XM_011545133 XP_011543435 XM_011545134 XP_011543436 NM_006244 NP_006235
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues. {ECO:0000269|PubMed:21329884}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:8703017}.
Tissue Specificity Highest expression in brain.
Top Pathways Oocyte meiosis, mRNA surveillance pathway, Dopaminergic synapse, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes

PP2A-B56-β (C-19) - sc-6117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PP2A-B56-β (C-19): sc-6117. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing cytoplasmic staining of Purkinje cells.

Anti-PPP2R5B antibody - ab1366 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-PPP2R5B antibody (ab1366) at 2 µg/ml + Human cerebellum lysate at 35 µg

Anti-PPP2R5B antibody - ab97295 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PPP2R5B antibody (ab97295) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-PPP2R5B antibody - ab167386 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PPP2R5B antibody (ab167386) at 1 µg/mlLane 1 : PPP2R5B transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-PPP2R5B antibody - C-terminal - ab177020 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-PPP2R5B antibody - C-terminal (ab177020) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : Jurkat total cell extract

Anti-PPP2R5B Antibody (aa434-497) - LS-C185804 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. PPP2R5B antibody. PPP2R5B antibody diluted at 1:1000.

Anti-PPP2R5B Antibody (aa484-497) - LS-C54561 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (0.5 ug/ml) of Mouse Brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-PPP2R5B Antibody (aa466-500) - LS-C344523 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from SK-N-MC cell line with PPP2R5B Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.

PPP2R5B Antibody - NBP1-88958 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PPP2R5B Antibody - NB100-850 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

PPP2R5B Antibody - NBP1-31043 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PPP2R5B Antibody [NBP1-31043] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE PPP2R5B antibody, antibody diluted at 1:1000.

PPP2R5B Antibody - H00005526-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-PPP2R5B (48-60) antibody produced in rabbit - SAB1100396 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PPP2R5B (48-60), <B>Cat. No. SAB1100396</B>: Immunofluorescence of HUVEC cells using Anti-PPP2R5B (48-60), SAB1100396 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PPP2R5B (181-195) antibody produced in rabbit - SAB1100397 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PPP2R5B (181-195), <B>Cat. No. SAB1100397</B>: Immunofluorescence of HUVEC cells using Anti-PPP2R5B (181-195), SAB1100397 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PPP2R5B antibody produced in rabbit - HPA036607 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PPP2R5B: <B>Cat. No. HPA036607</B>: Immunohistochemical staining of human cerebellum shows strong nuclear positivity in Purkinje cells.

B56-beta-isoform-Antibody - AF1133a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1133a (2 µg/ml) staining of Human Cerebellum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

PPP2R5B-Antibody-C-term - AP20958c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent image of SH-SY5Y cells stained with PPP2R5B Antibody (C-term)(Cat#AP20958c). AP20958c was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).

PPP2R5B antibody - orb73855 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:A431 whole cell lysate using PPP2R5B antibody

PPP2R5B Antibody (OAEB01538) - OAEB01538 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

PPP2R5B antibody - 70R-13002 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PPP2R5B antibody (OAGA00500) - OAGA00500 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PPP2R5B (C-term) antibody - AP15938PU-N from Acris Antibodies

Prices $310.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AP15938PU-N (2 µg/ml) staining of Human Cerebellum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

PPP2R5B (C-term) antibody - AP19059PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot analysis: AP19059PU-N PPP2R5B antibody staining of A431 whole cell lysate (30 µg) at 1/1000 dilution, 7.5% SDS PAGE.

PPP2R5B antibody - H00005526-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-PPP2R5B Antibody - AC21-0095 from Abcore

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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