CHST10

Gene Symbol CHST10
Entrez Gene 9486
Alt Symbol HNK-1ST, HNK1ST
Species Human
Gene Type protein-coding
Description carbohydrate sulfotransferase 10
Other Description HNK-1 sulfotransferase|huHNK-1ST
Swissprots O43529 Q53T18
Accessions AAX93044 CAJ75915 CBY88424 EAX01841 EAX01842 EAX01843 EAX01844 O43529 AF003827 AF033827 AAC04707 AF070594 AAC28651 AK297267 BAH12534 AK313241 BAG36052 AU124707 BC010441 AAH10441 BU849869 DA522916 DA732392 DQ891064 ABM81990 DQ894245 ABM85171 XM_011512207 XP_011510509 XM_011512208 XP_011510510 XM_011512209 XP_011510511 XM_011512210 XP_011510512 XM_011512211 XP_011510513 XM_011512212 XP_011510514 NM_004854 NP_004845
Function Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis. {ECO:0000269|PubMed:9478973}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe. {ECO:0000269|PubMed:9478973}.
Top Pathways Other types of O-glycan biosynthesis

CHST10-Over-expression-Lysate - LY14908a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CHST10 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CHST10 gene.

CHST10 overexpression lysate - LY417701 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CHST10 293 Cell Lysate - 408290 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Carbohydrate Sulfotransferase 10/CHST10 Overexpression Lysate (Native) - NBL1-09192 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CHST10 Overexpression Lysate (Adult Normal) [NBL1-09192] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CHST10.

CHST10 Over-expression Lysate Product - GWB-39C600 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human CHST10 Knockdown Stable Cell Line - CSC-DC003145 from Creative biogene

Category Cell Line
Species Human
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