CHST10

Gene Symbol CHST10
Entrez Gene 9486
Alt Symbol HNK-1ST, HNK1ST
Species Human
Gene Type protein-coding
Description carbohydrate sulfotransferase 10
Other Description HNK-1 sulfotransferase|huHNK-1ST
Swissprots O43529 Q53T18
Accessions AAX93044 CAJ75915 CBY88424 EAX01841 EAX01842 EAX01843 EAX01844 O43529 AF003827 AF033827 AAC04707 AF070594 AAC28651 AK297267 BAH12534 AK313241 BAG36052 AU124707 BC010441 AAH10441 BU849869 DA522916 DA732392 DQ891064 ABM81990 DQ894245 ABM85171 XM_011512207 XP_011510509 XM_011512208 XP_011510510 XM_011512209 XP_011510511 XM_011512210 XP_011510512 XM_011512211 XP_011510513 XM_011512212 XP_011510514 NM_004854 NP_004845
Function Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis. {ECO:0000269|PubMed:9478973}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe. {ECO:0000269|PubMed:9478973}.
Top Pathways Other types of O-glycan biosynthesis

HNK-1ST CRISPR/Cas9 KO Plasmid (h) - sc-409743 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNK-1ST HDR Plasmid (h) - sc-409743-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNK-1ST Double Nickase Plasmid (h) - sc-409743-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNK-1ST Double Nickase Plasmid (h2) - sc-409743-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNK-1ST CRISPR Activation Plasmid (h) - sc-409743-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNK-1ST CRISPR Activation Plasmid (h2) - sc-409743-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNK-1ST Lentiviral Activation Particles (h) - sc-409743-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNK-1ST Lentiviral Activation Particles (h2) - sc-409743-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNK-1ST siRNA (h) - sc-60794 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HNK-1ST shRNA Plasmid (h) - sc-60794-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HNK-1ST shRNA (h) Lentiviral Particles - sc-60794-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU052301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6104 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6104 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CHST10 siRNA (Human) - CRH6298 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHST10 - MBS8226093 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHST10 (NM_004854.4) - SHH263717 from Creative biogene

Category siRNA
Species Reactivities Human

CHST10 shRNA Plasmid (Human) - CHH6298 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CHST10 miRNA 3'UTR clone - MiUTR3H-08406 from Creative biogene

Species Reactivities Human
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