GALC

Gene Symbol	GALC
Entrez Gene	2581
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	galactosylceramidase
Other Description	GALCERase|galactocerebrosidase|galactocerebroside beta-galactosidase|galactosylceramide beta-galactosidase|galactosylceraminidase
Swissprots	J3KPP8 J3KN25 Q8J030 B7Z7Z2 B4DYN1 P54803 B4DKE8 B4DZJ8
Accessions	AAA80975 BAA24902 EAW81359 EAW81360 EAW81361 EAW81362 P54803 AI025909 AK294040 BAG57392 AK296530 BAG59160 AK302519 BAG63793 AK302683 BAH13778 AK302956 BAG64110 BC036518 AAH36518 BE501000 BQ015788 BU675449 CK299420 D25283 BAA04971 D25284 BAA04972 DA247447 DA323070 DA332567 DB366392 DC334180 DQ891232 ABM82158 DQ894416 ABM85342 H80485 L23116 AAA16645 XM_011536618 XP_011534920 NM_000153 NP_000144 NM_001201401 NP_001188330 NM_001201402 NP_001188331 NM_001037525
Function	Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. {ECO:0000269|PubMed:8281145, ECO:0000269|PubMed:8399327}.
Subcellular Location	Lysosome.
Tissue Specificity	Detected in urine. Detected in testis, brain and placenta (at protein level). Detected in kidney and liver. {ECO:0000269|PubMed:8399327}.
Top Pathways	Lysosome, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Galactosylceramidase full length protein - ab158488 from Abcam Category Protein Source Wheat germ Species Human

Human Galactosylceramidase full length protein - ab116728 from Abcam Category Protein Source Wheat germ Species Human

Human Galactosylceramidase protein fragment - ab158489 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human Galactosylceramidase/GALC Protein - H00002581-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Galactosylceramidase/GALC Protein - H00002581-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Galactosylceramidase/GALC Protein - H00002581-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Galactosylceramidase/GALC, CF - 7310-GH-005 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Met1-Arg685, with a C-terminal 6-His tag

GALC Blocking Peptide - 33R-5213 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Galactosylceramidase Protein - abx066720 from Abbexa Category Protein Source E.coli Species Human

Galactocerebrosidase - H00002581-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Galactocerebrosidase - H00002581-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Galactocerebrosidase - H00002581-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Galactocerebrosidase - H00002581-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Galactocerebrosidase - H00002581-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Galactocerebrosidase - H00002581-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Galactocerebrosidase - H00002581-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Galactosylceramidase (GALC), Human - 20-9184 from ARP American Research Products Category Protein Prices $589.00 Sizes 50 µg Source E.coli Species Human

GALC fusion protein - ag0483 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GALC fusion protein - ag3915 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human GALC, His-tagged - GALC-605H from Creative Biomart Category Protein Source CHO cells Species Human

Recombinant Galactosylceramidase (GALC) - RPG608Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Galactosylceramidase (GALC) - RPG608Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Galactosylceramidase (GALC) - RPG608Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Galactocerebrosidase(GALC) - CSB-YP009196HU CSB-EP009196HU CSB-BP009196HU CSB-MP009196HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Galactocerebrosidase protein - 80R-4346 from Fitzgerald Category Protein Prices $195.00 Sizes 50 µg Source E.coli

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