GALC

Gene Symbol GALC
Entrez Gene 2581
Alt Symbol -
Species Human
Gene Type protein-coding
Description galactosylceramidase
Other Description GALCERase|galactocerebrosidase|galactocerebroside beta-galactosidase|galactosylceramide beta-galactosidase|galactosylceraminidase
Swissprots J3KPP8 J3KN25 Q8J030 B7Z7Z2 B4DYN1 P54803 B4DKE8 B4DZJ8
Accessions AAA80975 BAA24902 EAW81359 EAW81360 EAW81361 EAW81362 P54803 AI025909 AK294040 BAG57392 AK296530 BAG59160 AK302519 BAG63793 AK302683 BAH13778 AK302956 BAG64110 BC036518 AAH36518 BE501000 BQ015788 BU675449 CK299420 D25283 BAA04971 D25284 BAA04972 DA247447 DA323070 DA332567 DB366392 DC334180 DQ891232 ABM82158 DQ894416 ABM85342 H80485 L23116 AAA16645 XM_011536618 XP_011534920 NM_000153 NP_000144 NM_001201401 NP_001188330 NM_001201402 NP_001188331 NM_001037525
Function Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. {ECO:0000269|PubMed:8281145, ECO:0000269|PubMed:8399327}.
Subcellular Location Lysosome.
Tissue Specificity Detected in urine. Detected in testis, brain and placenta (at protein level). Detected in kidney and liver. {ECO:0000269|PubMed:8399327}.
Top Pathways Lysosome, Sphingolipid metabolism

GALC CRISPR/Cas9 KO Plasmid (h) - sc-401025 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALC HDR Plasmid (h) - sc-401025-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALC Double Nickase Plasmid (h) - sc-401025-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALC Double Nickase Plasmid (h2) - sc-401025-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALC CRISPR Activation Plasmid (h) - sc-401025-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALC CRISPR Activation Plasmid (h2) - sc-401025-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALC Lentiviral Activation Particles (h) - sc-401025-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALC Lentiviral Activation Particles (h2) - sc-401025-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALC siRNA (h) - sc-60669 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GALC shRNA Plasmid (h) - sc-60669-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GALC shRNA (h) Lentiviral Particles - sc-60669-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU101741 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU011131 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9095 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10294 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10294

GALC siRNA (Human) - CRH1717 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GALC - MBS8218849 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GALC (NM_000153.3) - SHH298873 from Creative biogene

Category siRNA
Species Reactivities Human

GALC shRNA Plasmid (Human) - CHH1717 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GALC miRNA 3'UTR clone - MiUTR3H-08802 from Creative biogene

Species Reactivities Human
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