ASIC2

Gene Symbol	ASIC2
Entrez Gene	40
Alt Symbol	ACCN, ACCN1, ASIC2a, BNC1, BNaC1, MDEG, hBNaC1
Species	Human
Gene Type	protein-coding
Description	acid sensing (proton gated) ion channel 2
Other Description	acid-sensing (proton-gated) ion channel 2|acid-sensing ion channel 2|amiloride-sensitive cation channel 1, neuronal|brain sodium channel 1|mammalian degenerin homolog|neuronal amiloride-sensitive cation channel 1
Swissprots	Q16515 Q8N3E2 Q13553 Q6DJU1 E9PBX2
Accessions	CCQ43074 EAW80216 Q16515 AK127748 BAG54565 AK313043 BAG35875 AL834182 CAD38879 BC075042 AAH75042 BC075043 AAH75043 EU446513 ABZ92042 U50352 AAC50432 U53212 AAC50498 U57352 AAB49182 NM_001094 NP_001085 NM_183377 NP_899233
Function	Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes. {ECO:0000250}.
Tissue Specificity	Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary. {ECO:0000269|PubMed:10842183, ECO:0000269|PubMed:8631835}.
Top Pathways	Taste transduction, Inflammatory mediator regulation of TRP channels

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ACCN1 peptide - ab129538 from Abcam Category Peptide

ACCN1 / ASIC2 Antibody Blocking Peptide - LS-E12477 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACCN1 / ASIC2 Antibody Blocking Peptide - LS-E10010 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACCN1-Antibody-Center-Blocking-Peptide - BP9213c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACCN1 Blocking Peptide - 33R-5124 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACCN1 Blocking Peptide - 33R-3197 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACCN1 fusion protein - ag12301 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ACCN1 fusion protein - Ag12735 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Recombinant Human IL-9 (Carrier-free) - 21-8959 from Tonbo Biosciences Category Protein Prices $69.00, $179.00, $1,025.00, $3,100.00 Sizes 2 µg, 10 µg, 100 µg, 500 µg Source E. coli Species Human

Recombinant Human sCD40 Ligand (Carrier-free) - 21-7088 from Tonbo Biosciences Category Protein Prices $69.00, $418.00, $829.00 Sizes 10 µg, 50 µg, 500 µg Source E. coli Species Human

Recombinant Mouse IL-9 (Carrier-free) - 21-8952 from Tonbo Biosciences Category Protein Prices $69.00, $179.00, $1,025.00, $3,100.00 Sizes 2 µg, 10 µg, 100 µg, 500 µg Source E. coli Species Mouse

Recombinant Mouse sCD40 Ligand (Carrier-free) - 21-8512 from Tonbo Biosciences Category Protein Prices $69.00, $199.00, $625.00, $1,795.00 Sizes 5 µg, 25 µg, 100 µg, 500 µg Source E. coli Species Mouse

ASIC2 / ACCN1 (transcript variant 2) - TP310409 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ACCN1 Recombinant Protein Antigen - NBP2-14321PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ASIC2 Peptide, Human - M34GP01041H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more