Gene Symbol | Timp2 |
---|---|
Entrez Gene | 21858 |
Alt Symbol | D11Bwg1104e, Timp-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | tissue inhibitor of metalloproteinase 2 |
Other Description | metalloproteinase inhibitor 2|tissue inhibitor of metalloproteinases 2 |
Swissprots | P25785 |
Accessions | EDL34658 P25785 AK032818 BAC28038 AK081522 AK144236 AK178979 AK182277 AK192526 AK194045 AK194058 AK196263 AK206272 AK206457 AK209310 AK212870 AK215838 AK216347 AK217225 AY622854 AAT46409 BC021538 BC024962 BC029809 BC034375 BC035468 BC037235 BC049126 AAH49126 BC053932 BQ030835 M82858 AAA40445 M93954 AAA40446 X62622 CAA44491 NM_011594 NP_035724 |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. |
Subcellular Location | Secreted. |
Tissue Specificity | Detected in testis, retina, hippocampus and cerebral cortex. {ECO:0000269|PubMed:16985004}. |