Gene Symbol | Timp2 |
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Entrez Gene | 21858 |
Alt Symbol | D11Bwg1104e, Timp-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | tissue inhibitor of metalloproteinase 2 |
Other Description | metalloproteinase inhibitor 2|tissue inhibitor of metalloproteinases 2 |
Swissprots | P25785 |
Accessions | EDL34658 P25785 AK032818 BAC28038 AK081522 AK144236 AK178979 AK182277 AK192526 AK194045 AK194058 AK196263 AK206272 AK206457 AK209310 AK212870 AK215838 AK216347 AK217225 AY622854 AAT46409 BC021538 BC024962 BC029809 BC034375 BC035468 BC037235 BC049126 AAH49126 BC053932 BQ030835 M82858 AAA40445 M93954 AAA40446 X62622 CAA44491 NM_011594 NP_035724 |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. |
Subcellular Location | Secreted. |
Tissue Specificity | Detected in testis, retina, hippocampus and cerebral cortex. {ECO:0000269|PubMed:16985004}. |
TIMP-2 CRISPR/Cas9 KO Plasmid (m) - sc-423403 from Santa Cruz Biotechnology
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TIMP-2 HDR Plasmid (m) - sc-423403-HDR from Santa Cruz Biotechnology
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TIMP-2 Double Nickase Plasmid (m) - sc-423403-NIC from Santa Cruz Biotechnology
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TIMP-2 Double Nickase Plasmid (m2) - sc-423403-NIC-2 from Santa Cruz Biotechnology
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TIMP-2 CRISPR Activation Plasmid (m) - sc-423403-ACT from Santa Cruz Biotechnology
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TIMP-2 CRISPR Activation Plasmid (m2) - sc-423403-ACT-2 from Santa Cruz Biotechnology
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TIMP-2 Lentiviral Activation Particles (m) - sc-423403-LAC from Santa Cruz Biotechnology
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TIMP-2 Lentiviral Activation Particles (m2) - sc-423403-LAC-2 from Santa Cruz Biotechnology
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TIMP-2 siRNA (m) - sc-37275 from Santa Cruz Biotechnology
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TIMP-2 shRNA Plasmid (m) - sc-37275-SH from Santa Cruz Biotechnology
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TIMP-2 shRNA (m) Lentiviral Particles - sc-37275-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU090361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN42859 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42859 from Sigma-Aldrich
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shRNA set against Mouse Timp2(NM_011594.3) - SHL071712 from Creative biogene
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TIMP2 miRNA 3'UTR clone - MiUTR1M-11771 from Creative biogene
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