| Gene Symbol |
VEGFB
|
| Entrez Gene |
7423
|
| Alt Symbol |
VEGFL, VRF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vascular endothelial growth factor B
|
| Other Description |
VEGF-related factor
|
| Swissprots |
Q16528 P49765
|
| Accessions |
AAA91464 AAD14880 AAL79000 AAL79001 ABY87555 AGC09607 CAI84577 CAL33849 EAW74221 EAW74222 EAW74223 P49765 BC008818 AAH08818 BG031449 BM694361 BU730521 DQ892633 ABM83559 DQ895870 ABM86796 DQ895872 ABM86798 U43368 AAA91462 U43369 AAA91463 U48801 AAB06274 U52819 AAC50721 NM_001243733 NP_001230662 NM_003377 NP_003368
|
| Function |
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
|
| Subcellular Location |
Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
|
| Tissue Specificity |
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Focal adhesion, PI3K-Akt signaling pathway, Rap1 signaling pathway
|
![Western Blot: VEGFB Overexpression Lysate (Adult Normal) [NBL1-17713] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VEGFB.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9076_VEGFB%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17713-img0002.jpg)