GNAI1

Gene Symbol	GNAI1
Entrez Gene	2770
Alt Symbol	Gi
Species	Human
Gene Type	protein-coding
Description	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Other Description	Gi1 protein alpha subunit|adenylate cyclase-inhibiting G alpha protein|guanine nucleotide-binding protein G(i) subunit alpha-1
Swissprots	Q9UGA4 C9J3A4 P63096 B4E2V1 A8KA88 P11015 P31871 P04898 Q8TAN5 Q5U074
Accessions	AAA35893 AAC03418 EAW77009 EAW77010 EAW77011 EAW77012 P63096 AF055013 AAC09361 AF493905 AAM12619 AI878901 AK292953 BAF85642 AK304442 BAG65263 AL049933 CAB43212 AM393657 CAL38533 BC026326 AAH26326 BT019775 AAV38580 CD299597 DQ892385 ABM83311 DQ895598 ABM86524 DQ895599 ABM86525 M17219 AAA52581 NM_001256414 NP_001243343 NM_002069 NP_002060
Function	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division. {ECO:0000269|PubMed:17264214, ECO:0000269|PubMed:17635935}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:17635935}. Cell membrane {ECO:0000269|PubMed:17635935}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17635935}. Note=Localized at the plasma membrane throughout mitosis. Colocalizes with RIC8A and RGS14 at the plasma membrane (By similarity). Localizes in the centrosomes of interphase and mitotic cells, but not in centrosomes during cytokinesis. Detected at the cleavage furrow or the midbody. {ECO:0000250}.
Top Pathways	Circadian entrainment, Oxytocin signaling pathway, Estrogen signaling pathway, Adrenergic signaling in cardiomyocytes, Glutamatergic synapse

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

G Protein alpha Inhibitor 1+2 peptide - ab5006 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human G protein alpha inhibitor 1 full length protein - ab113585 from Abcam Category Protein Source E. coli Species Human

Human G protein alpha inhibitor 1 full length protein - ab132214 from Abcam Category Protein Source Wheat germ Species Human

Human G protein alpha inhibitor 1 full length protein - ab176669 from Abcam Category Protein Source E. coli Species Human

Human PAFR +Gia1ß1?2 fusion co-expressed full length protein - ab90726 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

G protein alpha inhibitor 1 Recombinant Protein - H00002770-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human G protein alpha inhibitor 1 Protein - NBP1-72466 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 50 µg, 250 µg Source E. coli Species Human

Human GNAI1 protein - orb168414 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

GNAI1 peptide - orb217342 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

GNAI1 Blocking Peptide - 33R-10215 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GNAI1 protein (His tag) - 80R-1980 from Fitzgerald Category Protein Prices $270.00 Sizes 50 µg Source E.coli

GNAI1 Blocking Peptide - abx062673 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Pig

G protein alpha inhibitor 1 (1-354, His-tag) - AR50049PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

G protein alpha inhibitor 1 (1-354, His-tag) - AR50049PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

G protein alpha inhibitor 1 - H00002770-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

G protein alpha inhibitor 1 - H00002770-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

G protein alpha inhibitor 1 control peptide - SP5158CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

GNAI1, 1-354aa, Human, His tag, E.coli - 01-P1224 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

GNAI1 fusion protein - Ag3290 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human GNAI1 Protein - BP001973-PRO-940 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

GNAI1, 1-354aa, Recombinant Protein - GWB-P0814H from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human GNAI1 Protein, His-tagged - GNAI1-28963TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Human Human GNAI1 - GNAI1-30630TH from Creative Biomart Category Protein

Recombinant Human Guanine Nucleotide Binding Protein (G protein), Alpha Inhibiting Activity Polypeptide 1, His-tagged - GNAI1-6873H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human GNAI1, GST-tagged - GNAI1-13346H from Creative Biomart Category Protein Source E.coli Species Human

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