ADSL

Gene Symbol ADSL
Entrez Gene 158
Alt Symbol AMPS, ASASE, ASL
Species Human
Gene Type protein-coding
Description adenylosuccinate lyase
Other Description adenylosuccinase
Swissprots Q5TI34 B0QY76 P30566 O75495
Accessions AAC83935 EAW60375 EAW60376 EAW60377 P30566 AF067853 AAC21560 AF067854 AAC21561 AK225042 AK291091 BAF83780 AK293722 BAG57152 AK298187 BAG60458 AK300705 BAG62384 AK308662 BC000253 AAH00253 BC018881 BP298407 CR456368 CAG30254 CU012935 CAK54366 CU013223 CAK54665 DQ893326 ABM84252 DQ896642 ABM87641 KJ534763 AHW56403 KJ535007 AHW56646 KJ535020 AHW56659 KJ535041 AHW56680 KJ535056 AHW56695 S60710 AAC60603 X65867 CAA46696 XM_011529976 XP_011528278 XM_011529977 XP_011528279 XM_011529978 XP_011528280 XM_011529979 XP_011528281 XM_011529980 XP_011528282 XM_011529981 XP_011528283 XM_011529982 XP_011528284 XR_937824 XR_937825 XR_937826 NM_000026 NP_000017 NM_001123378 NP_001116850
Function Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
Tissue Specificity Ubiquitously expressed. Both isoforms are produced by all tissues. Isoform 2 is 10-fold less abundant than isoform 1.
Top Pathways Purine metabolism, Alanine, aspartate and glutamate metabolism

ADSL (C-11) - sc-365623 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ADSL (C-11): sc-365623. Western blot analysis of ADSL expression in HeLa (A) and HCT 116 (B) whole cell lysates.

ADSL (D-12) - sc-86274 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
ADSL (D-12): sc-86274. Western blot analysis of ADSL expression in non-transfected: sc-117752 (A) and human ADSL transfected: sc-170309 (B) 293T whole cell lysates.

ADSL (H-300) - sc-367788 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ADSL (L-15) - sc-86275 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Adenylosuccinate Lyase antibody - ab151958 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Adenylosuccinate Lyase antibody (ab151958) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-Adenylosuccinate Lyase antibody - ab118421 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Adenylosuccinate Lyase antibody (ab118421) at 1/500 dilutionLane 1 : Human fetal heart lysateLane 2 : Human fetal liver lysateLane 3 : Human fetal kidney lysate

Anti-Adenylosuccinate Lyase antibody - ab67516 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Adenylosuccinate Lyase antibody (ab67516) at 1/500 dilutionLane 1 : Adenylosuccinate Lyase transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-Adenylosuccinate Lyase antibody [2D10] - ab119013 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D10
All lanes : Anti-Adenylosuccinate Lyase antibody [2D10] (ab119013) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY Adenylosuccinate Lyase cDNALysates/proteins at 5 µg per lane.

Anti-Adenylosuccinate Lyase antibody [EPR10746(B)] - ab154872 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10746(B)
Adenylosuccinate was immunoprecipitated from 1mg of NIH/3T3 (Mouse embyro fibroblast cells) whole cell extract with ab154872 at 1/40 dilution. Western blot was performed from the immunoprecipitate using ab154872 at 1/1000 dilution. VeriBlot for IP secondary antibody (HRP) (ab131366), was used as secondary antibody at 1/1500 dilution.Lane 1: NIH/3T3 whole cell extract, 10 µg (Input).Lane 2: ab154872 IP in NIH/3T3 whole cell extract.Lane 3: Rabbit monoclonal IgG (ab172730) instead of ab154872 in NIH/3T3 whole cell extract.Blocking and dilution buffer and concentration: 5% NFDM/TBST.Exposure time: 1 seconds 

Anti-Adenylosuccinate Lyase antibody [EPR10747(B)] - ab154182 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10747(B)
All lanes : Anti-Adenylosuccinate Lyase antibody [EPR10747(B)] (ab154182) at 1/1000 dilutionLane 1 : HeLa cell lysatesLane 2 : Jurkat cell lysatesLane 3 : HepG2 cell lysatesLane 4 : HCT-116 cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-ADSL / Adenylosuccinate Lyase Antibody - LS-C309344 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ADSL / Adenylosuccinate Lyase Antibody - LS-C306115 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ADSL / Adenylosuccinate Lyase Antibody (aa188-237) - LS-C135680 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ADSL antibody LS-C135680 Western blot of Fetal Muscle lysate.

Anti-ADSL / Adenylosuccinate Lyase Antibody - LS-C334610 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ADSL antibody.

Anti-ADSL / Adenylosuccinate Lyase Antibody (aa202-441) - LS-C178600 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Adenylosuccinate Lyase Antibody (2D10) - NBP2-03107 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D10
Western Blot: Adenylosuccinate Lyase Antibody (2D10) [NBP2-03107] Analysis of extracts (35ug) from 9 different cell lines by using anti-Adenylosuccinate Lyase monoclonal antibody.

Adenylosuccinate Lyase Antibody - NBP1-87406 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Adenylosuccinate Lyase Antibody - NBP2-15296 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Argininosuccinate Lyase Antibody - NBP1-87462 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Argininosuccinate Lyase Antibody [NBP1-87462] - Analysis in human cell line HepG2.

Adenylosuccinate Lyase Antibody - H00000158-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Adenylosuccinate Lyase Antibody [H00000158-B01P] - Analysis of ADSL expression in transfected 293T cell line by ADSL polyclonal antibody. Lane 1: ADSL transfected lysate(53.24 KDa). Lane 2: Non-transfected lysate.

Adenylosuccinate Lyase Antibody - 27820002 from Novus Biologicals

Prices $299.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Adenylosuccinate Lyase Antibody - NBP1-31934 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

Adenylosuccinate Lyase Antibody - H00000158-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Adenylosuccinate Lyase Antibody - bs-6352R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit

Anti-ADSL antibody produced in rabbit - SAB1410277 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ADSL: <B>Cat. No. SAB1410277</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~54.9 kDa using K-562 lysate.
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