| Gene Symbol |
Lilrb4
|
| Entrez Gene |
14728
|
| Alt Symbol |
CD85K, Gp49b, HM18, ILT3, LIR-5, gp49
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
leukocyte immunoglobulin-like receptor, subfamily B, member 4
|
| Other Description |
glycoprotein 49 B|leukocyte immunoglobulin-like receptor subfamily B member 4|mast cell surface glycoprotein Gp49B
|
| Swissprots |
Q64312 Q64281
|
| Accessions |
AAA17797 AAA17798 EDL05061 EDL05063 Q64281 AK089334 AK089372 AK155750 AK170368 AK170615 BC006591 AAH06591 BC099532 AAH99532 BY749633 U05264 AAA17796 U05266 AAA17799 XR_871431 XR_871432 XR_871433 NM_001291894 NP_001278823 NM_013532 NP_038560
|
| Function |
Receptor for class I MHC antigens. Involved in the down- regulation of the immune response and the development of tolerance. Interferes with TNFRSF5-signaling and NF-kappa-B up- regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment. {ECO:0000250}.
|