Gene Symbol | Lilrb4 |
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Entrez Gene | 14728 |
Alt Symbol | CD85K, Gp49b, HM18, ILT3, LIR-5, gp49 |
Species | Mouse |
Gene Type | protein-coding |
Description | leukocyte immunoglobulin-like receptor, subfamily B, member 4 |
Other Description | glycoprotein 49 B|leukocyte immunoglobulin-like receptor subfamily B member 4|mast cell surface glycoprotein Gp49B |
Swissprots | Q64312 Q64281 |
Accessions | AAA17797 AAA17798 EDL05061 EDL05063 Q64281 AK089334 AK089372 AK155750 AK170368 AK170615 BC006591 AAH06591 BC099532 AAH99532 BY749633 U05264 AAA17796 U05266 AAA17799 XR_871431 XR_871432 XR_871433 NM_001291894 NP_001278823 NM_013532 NP_038560 |
Function | Receptor for class I MHC antigens. Involved in the down- regulation of the immune response and the development of tolerance. Interferes with TNFRSF5-signaling and NF-kappa-B up- regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment. {ECO:0000250}. |
GP49B CRISPR/Cas9 KO Plasmid (m) - sc-420634 from Santa Cruz Biotechnology
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GP49B HDR Plasmid (m) - sc-420634-HDR from Santa Cruz Biotechnology
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GP49B Double Nickase Plasmid (m) - sc-420634-NIC from Santa Cruz Biotechnology
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GP49B Double Nickase Plasmid (m2) - sc-420634-NIC-2 from Santa Cruz Biotechnology
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GP49B CRISPR Activation Plasmid (m) - sc-420634-ACT from Santa Cruz Biotechnology
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GP49B CRISPR Activation Plasmid (m2) - sc-420634-ACT-2 from Santa Cruz Biotechnology
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GP49B Lentiviral Activation Particles (m) - sc-420634-LAC from Santa Cruz Biotechnology
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GP49B Lentiviral Activation Particles (m2) - sc-420634-LAC-2 from Santa Cruz Biotechnology
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GP49B siRNA (m) - sc-42886 from Santa Cruz Biotechnology
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GP49B shRNA Plasmid (m) - sc-42886-SH from Santa Cruz Biotechnology
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GP49B shRNA (m) Lentiviral Particles - sc-42886-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN34776 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34776 from Sigma-Aldrich
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LILRB4 siRNA (Mouse) - CRM1641 from Cohesion Biosciences
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shRNA set against Mouse LILRB4 (NM_013532.2) - SHH330319 from Creative biogene
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shRNA set against Mouse Lilrb4(NM_013532.2) - SHH149753 from Creative biogene
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Mouse LILRB4 siRNA - orb281117 from Biorbyt
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LILRB4 shRNA Plasmid (Mouse) - CHM1641 from Cohesion Biosciences
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LILRB4 miRNA 3'UTR clone - MiUTR1M-06646 from Creative biogene
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