EIF4E

Gene Symbol	EIF4E
Entrez Gene	1977
Alt Symbol	AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4E
Other Description	eIF-4E|eIF-4F 25 kDa subunit|eukaryotic translation initiation factor 4E-like 1|mRNA cap-binding protein
Swissprots	B7Z6V1 Q96E95 P06730 D6RCQ6
Accessions	AAB07114 CAI79364 CBL95069 CBY65608 CBY65610 EAX06077 EAX06078 EAX06079 EAX06080 EAX06081 P06730 AJ844638 AK295083 BAH11967 AK300982 BAH13387 AV708571 BC012611 AAH12611 BC035166 AAH35166 BC043226 AAH43226 BC107715 AAI07716 BM849222 CA419184 DC388666 DQ890728 ABM81654 DQ893903 ABM84829 KJ534830 AHW56470 M15353 AAC13647 XM_006714126 XP_006714189 XM_006714127 XP_006714190 NM_001130678 NP_001124150 NM_001130679 NP_001124151 NM_001968 NP_001959
Function	Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. {ECO:0000269|PubMed:16271312, ECO:0000269|PubMed:22578813}.
Subcellular Location	Cytoplasm, P-body {ECO:0000269|PubMed:20616046}. Cytoplasm {ECO:0000250}.
Top Pathways	Insulin signaling pathway, RNA transport, PI3K-Akt signaling pathway, mTOR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-EIF4E-cDNA-Clone - DC03466 from Abgent, a WuXi AppTec company Prices $292.95 Sizes 10 µg Species Human Accession BC012611

EIF4E - MBS1266653 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC012611

Human EIF4E cDNA clone(NM_001130679.1) - CDFH005802 from Creative Biomart Species Human Accession NM_001130679.1

Human EIF4E cDNA clone(NM_001130678.1) - CDFH005803 from Creative Biomart Species Human Accession NM_001130678.1

Human EIF4E ORF Clone(NM_001130678.1) - CDCR349575 from Creative Biomart Species Human Accession NM_001130678.1

Human EIF4E ORF Clone(NM_001130678.1) - CDCR349577 from Creative Biomart Species Human Accession NM_001130678.1

Human EIF4E ORF Clone(NM_001130679.1) - CDCR349578 from Creative Biomart Species Human Accession NM_001130679.1

Human EIF4E ORF Clone(NM_001130679.1) - CDCR349581 from Creative Biomart Species Human Accession NM_001130679.1

Human EIF4E ORF Clone(NM_001968.3) - CDCL162168 from Creative Biomart Species Human Accession NM_001968.3

Human eIF4E Gene cDNA Clone (full-length ORF Clone) - HG10033-M from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-tagged - HG10033-NY from Sino Biological Species Human Accession NM_001968.2

Human eIF4E natural ORF mammalian expression plasmid, C-GFPSpark tag - HG10033-ACG from Sino Biological Species Human Accession NM_001968.2

Human eIF4E natural ORF mammalian expression plasmid, N-Flag tag - HG10033-NF from Sino Biological Species Human Accession NM_001968.2

Human eIF4E natural ORF mammalian expression plasmid, C-Flag tag - HG10033-CF from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG10033-NM from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - HG10033-CM from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10033-M-F from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG10033-NH from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tag - HG10033-ACR from Sino Biological Species Human Accession NM_001968.2

Human eIF4E natural ORF mammalian expression plasmid, N-OFPSpark tag - HG10033-ANR from Sino Biological Species Human Accession NM_001968.2

Human eIF4E natural ORF mammalian expression plasmid, N-GFPSpark tag - HG10033-ANG from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG10033-CY from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-tagged - HG10033-CH from Sino Biological Species Human Accession NM_001968.2

Human eIF4E Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10033-UT from Sino Biological Species Human Accession NM_001968.2

Human EIF4E ORF clone (NM_001130679.1) - CDCR042022 from Creative biogene Species Human

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