Serpine1

Gene Symbol Serpine1
Entrez Gene 18787
Alt Symbol PAI-1, PAI1, Planh1
Species Mouse
Gene Type protein-coding
Description serine (or cysteine) peptidase inhibitor, clade E, member 1
Other Description PAI|Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI)|endothelial plasminogen activator inhibitor|nexin, plasminogen activator inhibitor type 1|plasminogen activator inhibitor 1|plasminogen activator inhibitor, type I|serine (or cysteine) proteinase inhibitor, clade E, member 1|serpin E1
Swissprots P22777
Accessions EDL19286 EDL19287 P22777 AK040662 BC054091 AAH54091 GQ872458 ACX48997 GQ872459 ACX48998 M33960 AAA39887 NM_008871 NP_032897
Function Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis (By similarity). {ECO:0000250}.
Subcellular Location Secreted.
Top Pathways p53 signaling pathway, Complement and coagulation cascades, Chagas disease (American trypanosomiasis), Hippo signaling pathway

PAI-1 CRISPR/Cas9 KO Plasmid (m) - sc-422287 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 HDR Plasmid (m) - sc-422287-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 Double Nickase Plasmid (m) - sc-422287-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 Double Nickase Plasmid (m2) - sc-422287-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 CRISPR Activation Plasmid (m) - sc-422287-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 CRISPR Activation Plasmid (m2) - sc-422287-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 Lentiviral Activation Particles (m) - sc-422287-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 Lentiviral Activation Particles (m2) - sc-422287-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 siRNA (m) - sc-36180 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

PAI-1 shRNA Plasmid (m) - sc-36180-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

PAI-1 shRNA (m) Lentiviral Particles - sc-36180-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU041501 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN41002 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND41002 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PAI-1 CRISPR/Cas9 KO Plasmid (m2) - sc-422287-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PAI-1 HDR Plasmid (m2) - sc-422287-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

shRNA set against Mouse SERPINE1 (NM_008871.2) - SHH405352 from Creative biogene

Category siRNA
Species Reactivities Mouse
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