Gene Symbol |
Grm7
|
Entrez Gene |
108073
|
Alt Symbol |
6330570A01Rik, BB176677, C030018L03, E130018M02Rik, Gpr1g, Gprc1g, mGluR7
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
glutamate receptor, metabotropic 7
|
Other Description |
G protein-coupled receptor GRM7|G protein-coupled receptor, family C, group 1, member G|mGlu7a receptor|metabotropic glutamate receptor 7
|
Swissprots |
Q68ED2
|
Accessions |
EDK99419 EDK99420 EDK99421 Q68ED2 AK032068 AK047160 BAC32974 AK047733 BAC33142 AK053447 BAC35388 AY255607 AAO85119 BC080315 AAH80315 XM_006505296 XP_006505359 XM_006505297 XP_006505360 XM_006505298 XP_006505361 XM_006505299 XP_006505362 XM_006505300 XP_006505363 XM_006505301 XP_006505364 XM_006505302 XP_006505365 XR_377401 XR_868841 XR_868842 XR_868843 NM_177328 NP_796302
|
Function |
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Top Pathways |
Glutamatergic synapse, Neuroactive ligand-receptor interaction
|