Gene Symbol | Grm7 |
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Entrez Gene | 108073 |
Alt Symbol | 6330570A01Rik, BB176677, C030018L03, E130018M02Rik, Gpr1g, Gprc1g, mGluR7 |
Species | Mouse |
Gene Type | protein-coding |
Description | glutamate receptor, metabotropic 7 |
Other Description | G protein-coupled receptor GRM7|G protein-coupled receptor, family C, group 1, member G|mGlu7a receptor|metabotropic glutamate receptor 7 |
Swissprots | Q68ED2 |
Accessions | EDK99419 EDK99420 EDK99421 Q68ED2 AK032068 AK047160 BAC32974 AK047733 BAC33142 AK053447 BAC35388 AY255607 AAO85119 BC080315 AAH80315 XM_006505296 XP_006505359 XM_006505297 XP_006505360 XM_006505298 XP_006505361 XM_006505299 XP_006505362 XM_006505300 XP_006505363 XM_006505301 XP_006505364 XM_006505302 XP_006505365 XR_377401 XR_868841 XR_868842 XR_868843 NM_177328 NP_796302 |
Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Glutamatergic synapse, Neuroactive ligand-receptor interaction |
mGluR-7 CRISPR/Cas9 KO Plasmid (m) - sc-430799 from Santa Cruz Biotechnology
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mGluR-7 HDR Plasmid (m) - sc-430799-HDR from Santa Cruz Biotechnology
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mGluR-7 Double Nickase Plasmid (m) - sc-430799-NIC from Santa Cruz Biotechnology
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mGluR-7 Double Nickase Plasmid (m2) - sc-430799-NIC-2 from Santa Cruz Biotechnology
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mGluR-7 CRISPR Activation Plasmid (m) - sc-430799-ACT from Santa Cruz Biotechnology
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mGluR-7 CRISPR Activation Plasmid (m2) - sc-430799-ACT-2 from Santa Cruz Biotechnology
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mGluR-7 Lentiviral Activation Particles (m) - sc-430799-LAC from Santa Cruz Biotechnology
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mGluR-7 Lentiviral Activation Particles (m2) - sc-430799-LAC-2 from Santa Cruz Biotechnology
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mGluR-7 siRNA (m) - sc-61039 from Santa Cruz Biotechnology
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mGluR-7 shRNA Plasmid (m) - sc-61039-SH from Santa Cruz Biotechnology
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mGluR-7 shRNA (m) Lentiviral Particles - sc-61039-V from Santa Cruz Biotechnology
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MISSION® Long Non-Coding esiRNA - EMNC009781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN32867 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32867 from Sigma-Aldrich
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GRM7 siRNA (Mouse) - CRN0903 from Cohesion Biosciences
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GRM7 - MBS8219493 from MyBioSource
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shRNA set against Mouse GRM7 (NM_177328.3) - SHH308162 from Creative biogene
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shRNA set against Mouse Grm7(NM_177328.3) - SHH105779 from Creative biogene
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Mouse GRM7 siRNA - orb290378 from Biorbyt
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GRM7 shRNA Plasmid (Mouse) - CHN0903 from Cohesion Biosciences
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GRM7 miRNA 3'UTR clone - MiUTR1M-05394 from Creative biogene
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