SGPL1

Gene Symbol	SGPL1
Entrez Gene	8879
Alt Symbol	S1PL, SPL
Species	Human
Gene Type	protein-coding
Description	sphingosine-1-phosphate lyase 1
Other Description	SP-lyase 1|SPL 1|hSPL|sphingosine-1-phosphate aldolase
Swissprots	Q7Z732 Q9ULG8 O95470 B2RBD4 Q9UN89
Accessions	CAM35395 EAW54414 O95470 AB033078 BAA86566 AF144638 AAD44755 AJ011304 CAA09590 AK023873 AK308610 AK314615 BAG37181 BC031338 BC041567 BC051238 BC052991 AAH52991 BC068061 BP314104 XM_005270263 XP_005270320 XM_006718053 XP_006718116 XM_011540316 XP_011538618 XM_011540317 XP_011538619 XM_011540318 XP_011538620 XM_011540319 XP_011538621 NM_003901 NP_003892
Function	Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. {ECO:0000269|PubMed:11018465, ECO:0000269|PubMed:14570870, ECO:0000269|PubMed:24809814}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Tissue Specificity	Found in liver and kidney. {ECO:0000269|PubMed:11018465}.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse SGPL1 ELISA Kit (Sandwich ELISA) - LS-F8770 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.156-10 ng/ml

Mouse SGPL1 ELISA Kit (Sandwich ELISA) - LS-F12595 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Sphingosine-1-phosphate lyase 1, SGPL1, Human, ELISA Kit - E15015h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 78-5000 pg/mL

Sphingosine 1 Phosphate Lyase 1 (SGPL1), ELISA Kit - MBS2021123 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.055ng/mL. Range 0.156-10ng/mL

ELISA Kit for Sphingosine 1 Phosphate Lyase 1 (SGPL1) - SEE691Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Rat SGPL1 ELISA Kit (Custom ELISA) - LS-F17635 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human Sphingosine-1-phosphate lyase 1 ELISA Kit - abx251015 from Abbexa Category ELISA Kit Range 78 pg/ml - 5000 pg/ml

Human Sphingosine-1-phosphate lyase 1 ELISA Kit - EKE54659 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 36 pg/ml Range 78-5000 pg/mL

SGPL1 ELISA Kit (Human) (OKEH02435) - OKEH02435 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 36 pg/mL Range 78 - 5,000 pg/mL

Human SGPL1 ELISA Kit - E036455 from Biobool Category ELISA Kit

Human Sphingosine-1-phosphate lyase 1 ELISA Kit - EK3566 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Sensitivity less than 36 pg/ml Range 78-5000 pg/mL

Sphingosine-1-phosphate lyase 1, ELISA Kit - MBS9427400 from MyBioSource Category ELISA Kit Prices $670.00 Sizes 96 tests Sensitivity Less than 36 pg/mL Range 78-5000 pg/mL

Sphingosine-1-phosphate lyase 1, ELISA Kit - MBS2881998 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 78.0 pg/mL -5000 pg/mL.

Sphingosine-1-phosphate lyase 1, ELISA Kit - MBS765872 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Sphingosine 1 Phosphate Lyase 1 (SGPL1), ELISA Kit - MBS9374696 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse SGPL1 ELISA Kit (Sandwich ELISA) - LS-F35305 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.094 Range 0.156-10 ng/ml

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