SGPL1

Gene Symbol	SGPL1
Entrez Gene	8879
Alt Symbol	S1PL, SPL
Species	Human
Gene Type	protein-coding
Description	sphingosine-1-phosphate lyase 1
Other Description	SP-lyase 1|SPL 1|hSPL|sphingosine-1-phosphate aldolase
Swissprots	Q7Z732 Q9ULG8 O95470 B2RBD4 Q9UN89
Accessions	CAM35395 EAW54414 O95470 AB033078 BAA86566 AF144638 AAD44755 AJ011304 CAA09590 AK023873 AK308610 AK314615 BAG37181 BC031338 BC041567 BC051238 BC052991 AAH52991 BC068061 BP314104 XM_005270263 XP_005270320 XM_006718053 XP_006718116 XM_011540316 XP_011538618 XM_011540317 XP_011538619 XM_011540318 XP_011538620 XM_011540319 XP_011538621 NM_003901 NP_003892
Function	Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. {ECO:0000269|PubMed:11018465, ECO:0000269|PubMed:14570870, ECO:0000269|PubMed:24809814}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Tissue Specificity	Found in liver and kidney. {ECO:0000269|PubMed:11018465}.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SGPL1 full length protein - ab160241 from Abcam Category Protein Source Wheat germ Species Human

Human SGPL1 protein fragment - ab160242 from Abcam Category Protein Source Wheat germ Species Human

SGPL1 Antibody Blocking Peptide - LS-E1901 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SGPL1 Antibody Blocking Peptide - LS-E24033 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SGPL1 Protein - H00008879-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SGPL1 Recombinant Protein - H00008879-P01 from Novus Biologicals Category Protein

SGPL1-Antibody-N-term-Blocking-peptide - BP12736a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human SGPL1 Protein - abx069143 from Abbexa Category Protein Source E.coli Species Human

SGPL1 - H00008879-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

SGPL1 - H00008879-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

SGPL1 - H00008879-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

SGPL1 - H00008879-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SGPL1 - H00008879-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Sphingosine 1 Phosphate Lyase 1 (SGPL1), Human - 20-8968 from ARP American Research Products Category Protein Prices $479.00 Sizes 50 µg Source E.coli Species Human

Sphingosine-1-phosphate lyase1, Active Human Recombinant Protein - GWB-1A5A57 from Genway Biotech Category Protein Prices $600.00 Sizes 10 µg Species Human

Recombinant Human SGPL1, His-tagged - SGPL1-501H from Creative Biomart Category Protein Source Sf9 cell.

Recombinant Sphingosine 1 Phosphate Lyase 1 (SGPL1) - RPE691Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Sphingosine 1 Phosphate Lyase 1 (SGPL1) - RPE691Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Sphingosine 1 Phosphate Lyase 1 (SGPL1) - RPE691Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Sphingosine 1 Phosphate Lyase 1 (SGPL1) - RPE691Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Sphingosine-1-phosphate lyase 1(SGPL1) - CSB-YP021197HU CSB-EP021197HU CSB-BP021197HU CSB-MP021197HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SGPL1 - TP308705 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SGPL1 Recombinant Protein Antigen - NBP2-48552PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SGPL1 Peptide, Human - M34GP14144H from Creative Peptides Category Peptide Source Synthetic. Species Human

SGPL1 Recombinant Protein Antigen - NBP2-48495PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

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