ABCC6

Gene Symbol	ABCC6
Entrez Gene	368
Alt Symbol	ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7
Species	Human
Gene Type	protein-coding
Description	ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Other Description	ATP-binding cassette sub-family C member 6|anthracycline resistance-associated protein|multi-specific organic anion transporter E|multidrug resistance-associated protein 6
Swissprots	A8Y988 A2RRN8 P78420 A8KIG6 E7ESW8 Q8TCY8 O95255 Q9UMZ7
Accessions	AAC15785 EAW53950 EAW53951 EAW53952 O95255 AF076622 AAC79696 AF168791 AAD51293 AI074459 AK298295 BAG60553 AM711638 CAN84639 AM774324 CAO81806 AY078405 AAL83711 BC050733 AAH50733 BC131732 AAI31733 DC361874 XM_011522479 XP_011520781 XM_011522480 XP_011520782 XM_011522481 XP_011520783 XM_011522482 XP_011520784 XM_011546696 XP_011544998 XM_011546697 XP_011544999 XR_932836 XR_932837 XR_932838 XR_951901 XR_951902 XR_951903 NM_001079528 NP_001072996 NM_001171 NP_001162
Function	Isoform 1: May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS). {ECO:0000269|PubMed:11880368}.
Subcellular Location	Isoform 1: Basolateral cell membrane {ECO:0000269|PubMed:12901863, ECO:0000269|PubMed:23625951}; Multi- pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12901863, ECO:0000269|PubMed:23625951}.
Tissue Specificity	Expressed in kidney and liver. Very low expression in other tissues.
Top Pathways	ABC transporters

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MRP6 (H-70) - sc-25505 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

MRP6 (N-20) - sc-5783 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

MRP6 (M6II-7) - sc-57528 from Santa Cruz Biotechnology Prices $279.00 Sizes 500 µl supernatant Host Rat Clonality Monoclonal

MRP6 (M6II-21) - sc-57527 from Santa Cruz Biotechnology Prices $279.00 Sizes 500 µl supernatant Host Rat Clonality Monoclonal

MRP6 (M6II-31) - sc-59618 from Santa Cruz Biotechnology Prices $279.00 Sizes 500 µl supernatant Host Rat Clonality Monoclonal

Anti-MRP6 antibody - ab186340 from Abcam Host Rabbit Clonality Polyclonal

Anti-MRP6 antibody - ab167564 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-MRP6 antibody - ab54826 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-MRP6 antibody [M6II-7] - ab130460 from Abcam Prices $370.00 Sizes 250 µl Host Rat Clonality Monoclonal Clone M6II-7

Anti-MRP6 antibody - C-terminal - ab200084 from Abcam Host Rabbit Clonality Polyclonal

Anti-ABCC6 / MRP6 Antibody (aa764-964) - LS-C25530 from LifeSpan Bioscience Host Rat Clonality Monoclonal

Anti-ABCC6 / MRP6 Antibody (aa764-964, clone M6II-21) - LS-C124155 from LifeSpan Bioscience Prices $665.00 Sizes 1 ml Host Rat Clonality Monoclonal Clone M6II-21

Anti-ABCC6 / MRP6 Antibody (aa764-964, clone M6II-7) - LS-C124157 from LifeSpan Bioscience Prices $665.00 Sizes 1 ml Host Rat Clonality Monoclonal Clone M6II-7

Anti-ABCC6 / MRP6 Antibody (clone M6II-31) - LS-C134868 from LifeSpan Bioscience Prices $325.00 Sizes 1 ml Host Rat Clonality Monoclonal Clone M6II-31

Anti-ABCC6 / MRP6 Antibody (clone M6II-7) - LS-C202629 from LifeSpan Bioscience Prices $325.00 Sizes 1 ml Host Rat Clonality Monoclonal Clone M6II-7

Anti-ABCC6 / MRP6 Antibody (clone M6II-21) - LS-C202630 from LifeSpan Bioscience Prices $325.00 Sizes 1 ml Host Rat Clonality Monoclonal Clone M6II-21

Anti-ABCC6 / MRP6 Antibody - LS-C306024 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-ABCC6 / MRP6 Antibody (clone 1E6) - LS-C196680 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1E6

MRP6 Antibody (5D8) - H00000368-M02 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5D8

MRP6 Antibody (1E6.) - H00000368-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1E6.

MRP6 Antibody - H00000368-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

MRP6 Antibody - H00000368-A01 from Novus Biologicals Host Mouse Clonality Polyclonal

Anti-ABCC6 antibody produced in mouse - SAB1405476 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Monoclonal Anti-ABCC6 antibody produced in mouse - WH0000368M1 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1E6

ABCC6-Antibody-monoclonal-M02 - AT1008a from Abgent, a WuXi AppTec company Prices $315.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5D8

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